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| | ASP-ALA-PHE-VAL-BETA-ALA-LEU-MET-NH2 Basic information |
| Product Name: | ASP-ALA-PHE-VAL-BETA-ALA-LEU-MET-NH2 | | Synonyms: | [ALA5, BETA-ALA8]-ALPHA-NEUROKININ FRAGMENT 4-10;[ALA5, BETA-ALA8]-NEUROKININ A (4-10);DAFV-(BETA-A)-LM-NH2;H-ASP-ALA-PHE-VAL-BETA-ALA-LEU-MET-NH2;ASP-ALA-PHE-VAL-BETA-ALA-LEU-MET-NH2;(ala5;(ALA5, B-ALA8)-A-NEUROKININ*FRAGMENT 4-1 0;[ala5, β-ala8]-α-neurokinin fragment 4-10 | | CAS: | 127633-71-0 | | MF: | C35H56N8O9S | | MW: | 764.93 | | EINECS: | | | Product Categories: | peptide | | Mol File: | 127633-71-0.mol |  |
| | ASP-ALA-PHE-VAL-BETA-ALA-LEU-MET-NH2 Chemical Properties |
| Boiling point | 1193.404±65.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.234±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | storage temp. | −20°C | | pka | 3.712±0.10(predicted) |
| | ASP-ALA-PHE-VAL-BETA-ALA-LEU-MET-NH2 Usage And Synthesis |
| Uses | (β-Ala8)-Neurokinin A (4-10), a neuropeptide, is a potent and selective NK-2 tachykinin receptor (Neurokinin Receptor) agonist[1]. | | in vivo | (β-Ala8)-Neurokinin A (4-10) (2 μg/kg; i.v.) increases colonic tone in conscious female dogs[2]. | | References | [1] C A Maggi, et al. In vivo pharmacology of [beta Ala8]neurokinin A-(4-10), a selective NK-2 tachykinin receptor agonist. Eur J Pharmacol. 1990 Feb 20;177(1-2):81-6. DOI:10.1016/0014-2999(90)90552-h
[2] G Basilisco, et al. A selective NK-2 antagonist blocks the increase of canine colonic tone and ileal contractions induced by the NK-2 selective receptor agonist, [beta Ala8] neurokinin A-(4-10). Aliment Pharmacol Ther. 1994 Oct;8(5):527-33. DOI:10.1111/j.1365-2036.1994.tb00326.x |
| | ASP-ALA-PHE-VAL-BETA-ALA-LEU-MET-NH2 Preparation Products And Raw materials |
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