5-{4-[(2R,6R)-13-methoxy-8-oxa-4-azatricyclo[7.4.0.0^{2,6}]trideca-1(9),10,12-trien-4-yl]butyl}-12-phenyl-8-thia-3,5,10,13-tetraazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),10,12-tetraene-4,6-dione hydrochloride
| 中文名称 | 5-{4-[(2R,6R)-13-methoxy-8-oxa-4-azatricyclo[7.4.0.0^{2,6}]trideca-1(9),10,12-trien-4-yl]butyl}-12-phenyl-8-thia-3,5,10,13-tetraazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),10,12-tetraene-4,6-dione hydrochloride |
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| 中文同义词 | 化合物 FIDUXOSIN HYDROCHLORIDE |
| 英文名称 | 5-{4-[(2R,6R)-13-methoxy-8-oxa-4-azatricyclo[7.4.0.0^{2,6}]trideca-1(9),10,12-trien-4-yl]butyl}-12-phenyl-8-thia-3,5,10,13-tetraazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),10,12-tetraene-4,6-dione hydrochloride |
| 英文同义词 | 5-{4-[(2R,6R)-13-methoxy-8-oxa-4-azatricyclo[7.4.0.0^{2,6}]trideca-1(9),10,12-trien-4-yl]butyl}-12-phenyl-8-thia-3,5,10,13-tetraazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),10,12-tetraene-4,6-dione hydrochloride |
| CAS号 | 208992-74-9 |
| 分子式 | C30H30ClN5O4S |
| 分子量 | 592.11 |
| EINECS号 | 633-806-1 |
| 相关类别 | |
| Mol文件 | 208992-74-9.mol |
| 结构式 | ![5-{4-[(2R,6R)-13-methoxy-8-oxa-4-azatricyclo[7.4.0.0^{2,6}]trideca-1(9),10,12-trien-4-yl]butyl}-12-phenyl-8-thia-3,5,10,13-tetraazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),10,12-tetraene-4,6-dione hydrochloride 结构式](CAS/20211123/GIF/208992-74-9.gif) |
5-{4-[(2R,6R)-13-methoxy-8-oxa-4-azatricyclo[7.4.0.0^{2,6}]trideca-1(9),10,12-trien-4-yl]butyl}-12-phenyl-8-thia-3,5,10,13-tetraazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),10,12-tetraene-4,6-dione hydrochloride 性质
| 熔点 | 178-185 °C |
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5-{4-[(2R,6R)-13-methoxy-8-oxa-4-azatricyclo[7.4.0.0^{2,6}]trideca-1(9),10,12-trien-4-yl]butyl}-12-phenyl-8-thia-3,5,10,13-tetraazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),10,12-tetraene-4,6-dione hydrochloride 用途与合成方法
Fiduxosin hydrochloride (ABT 980) 是一种 α1-adrenoceptor 拮抗剂，对 α1a-adrenoceptor，α1b-adrenoceptor 和 α1d-adrenoceptor 的 Ki 值分别为 0.160 nM，24.9 nM 和 0.920 nM。