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| | SIRT5 inhibitor Basic information |
| Product Name: | SIRT5 inhibitor | | Synonyms: | SIRT5 inhibitor;SIRT5 inhibitor 1;3-(3-((S)-6-(((S)-1-(Cyclobutylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)amino)-5-((3-fluorophenyl)sulfonamido)-6-oxohexyl)thioureido)propanoic acid;SIRT-5 inhibitor 1,SIRT5 inhibitor 1;SIRT5 inhibitor 1, 10 mM in DMSO | | CAS: | 2166487-21-2 | | MF: | C31H39FN6O6S2 | | MW: | 674.81 | | EINECS: | | | Product Categories: | | | Mol File: | 2166487-21-2.mol |  |
| | SIRT5 inhibitor Chemical Properties |
| density | 1.41±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO : 125 mg/mL (185.24 mM) | | form | Solid | | pka | 4.34±0.10(Predicted) | | color | White to off-white |
| | SIRT5 inhibitor Usage And Synthesis |
| Uses | SIRT5 inhibitor 1 is a potent Human Sirtuin 5 deacylase inhibitor, with an IC50 of 0.11 μM. | | References | [1] Rajabi N, et al. Mechanism-Based Inhibitors of the Human Sirtuin 5 Deacylase: Structure-Activity Relationship, Biostructural, and Kinetic Insight. Angew Chem Int Ed Engl. 2017 Nov 20;56(47):14836-14841. DOI:10.1002/anie.201709050 |
| | SIRT5 inhibitor Preparation Products And Raw materials |
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