205391-02-2
| 中文名称 | 205391-02-2 |
|---|---|
| 中文同义词 | 4,5-二氨基荧光素二乙酸酯;化合物 T18966;DAF2DA|||DAF 2DA|||5,6-DIAMINOFLUORESCEIN DIACETAT;化合物 DAF-2DA;DAF-2 DA (DMSO SOLUTION),FLUORESCENT NITRIC OXIDE PROBE;DAF-2 DA,FLUORESCENT NITRIC OXIDE PROBE;4,5-二氨基荧光素双乙酸酯;DAF-2 DA(4,5-DIAMINOFLUORESCEIN DIACETATE) 一氧化氮检测探针 |
| 英文名称 | 4,5-DIAMINOFLUORESCEIN DIACETATE |
| 英文同义词 | DAF-2 DA - CAS 205391-02-2 - Calbiochem;4,5-DIAMINOFLUORESCEIN DIACETATE;4,5-DIAMINOFLUORORESCEIN DIACETATE;5,6-DIAMINOFLUORESCEIN DIACETATE;2-(3,6-DIACETYLOXY-9H-XANTHEN-9-YL)-4,5-DIAMINO-BENZOIC ACID;DAF-2 DA;DAF-2 DA, CELL PERMEABLE;DAF-2 DIACETATE |
| CAS号 | 205391-02-2 |
| 分子式 | C24H18N2O7 |
| 分子量 | 446.41 |
| EINECS号 | |
| 相关类别 | 荧光探针，标记，颗粒和染色 |
| Mol文件 | 205391-02-2.mol |
| 结构式 |  |
205391-02-2 性质
| 沸点 | 719.0±60.0 °C(Predicted) |
|---|---|
| 密度 | 1.54±0.1 g/cm3(Predicted) |
| 闪点 | 87 °C |
| 储存条件 | 2-8°C |
| 溶解度 | 二甲基亚砜：<2mg/毫升 |
| 形态 | 淡黄色溶液 |
| 酸度系数(pKa) | 2.92±0.20(Predicted) |
| 颜色 | 白色 |
| 主要应用 | 诊断试剂生产 血液学 组织学 |
| InChI | 1S/C24H18N2O7/c1-11(27)30-13-3-5-16-21(7-13)32-22-8-14(31-12(2)28)4-6-17(22)24(16)18-10-20(26)19(25)9-15(18)23(29)33-24/h3-10H,25-26H2,1-2H3 |
| InChIKey | PTSUYDXEEKDBQU-UHFFFAOYSA-N |
| SMILES | O=C1OC2(C3=C(OC4=C2C=CC(OC(C)=O)=C4)C=C(OC(C)=O)C=C3)C5=C1C=C(N)C(N)=C5 |
DAF-2DA (5,6-Diaminofluorescein diacetat) 是测量 NO 最广泛使用的一种荧光探针。
Nitric oxide is a free radical signal molecule. Various methods are available for measurement of NO. Out of all methods, fluorescent probes to localize NO is very widely used method. Diaminofl uorescein in diacetate form (DAF-2DA) is most widely probe for NO measurement. This method is based on application of 4,5-diaminofl uorescein diacetate (DAF-2DA) which is actively diffused into cells, once taken up by cells cytoplasmic esterases cleave the acetate groups to generate 4,5-diaminofl uorescein; DAF-2. The generated DAF-2 can readily react with N 2 O 3 , which is an oxidation product of NO to generate the highly fluorescent DAF-2T (triazolofl uorescein).
安全信息
| WGK Germany | 3 |
|---|---|
| 存储类别 | 11 - 可燃固体 |
| 提供商 | 语言 |
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英文
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| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2026/06/05 | HY-D0032 | 205391-02-2 DAF-2DA | 205391-02-2 | 100 μg | 1300元 |
| 2026/06/05 | HY-D0032 | 205391-02-2 DAF-2DA | 205391-02-2 | 250 μg | 2600元 |