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| | Cortistatin 14 Basic information |
| Product Name: | Cortistatin 14 | | Synonyms: | Cortistatin 14, human, rat(Synonyms: CST-14, human, rat);CST-14, human, rat | | CAS: | 193829-96-8 | | MF: | C81H113N19O19S2 | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![Cortistatin 14 Structure]() |
| | Cortistatin 14 Chemical Properties |
| storage temp. | Desiccate at -20°C | | form | Powder | | color | White to off-white | | Water Solubility | Soluble to 0.70 mg/ml in water | | Sequence | Pro-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Ser-Ser-Cys-Lys (Disulfide bridge: Cys2-Cys13) |
| | Cortistatin 14 Usage And Synthesis |
| Uses | Cortistatin 14, mouse, rat (CST-14, human, rat), a neuropeptide with neuronal depressant and sleep modulating properties, can bind to all five cloned somatostatin receptors (SSTRs) and ghrelin receptor to exert its biological activities and co-exists with GABA within the cortex and hippocampus[1][2]. | | storage | Store at -20°C | | References | [1] Jiang J, et al. Centrally Administered Cortistation-14 Induces Antidepressant-Like Effects in Mice via MediatingGhrelin and GABAA Receptor Signaling Pathway. Front Pharmacol. 2018 Jul 19;9:767. DOI:10.3389/fphar.2018.00767
[2] de Lecea L, et al. A cortical neuropeptide with neuronal depressant and sleep-modulating properties. Nature. 1996 May 16;381(6579):242-5. DOI:10.1038/381242a0 |
| | Cortistatin 14 Preparation Products And Raw materials |
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