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2-Thiophenesulfonyl chloride

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2-Thiophenesulfonyl chloride manufacturers

2-Thiophenesulfonyl chloride Basic information
Product Name:2-Thiophenesulfonyl chloride
Synonyms:Thiophene-2-sulphonyl chloride 97%;2-(Chlorosulfonyl)-thiophene;2-Thiophene Sulfonylcloride;2-THIOPHENESULFONYLCHLORIDE,96%;2-Thiophenesulfonic acid chloride;Thiophene-2-sulfonic acid chloride;2-Thiophenesulfonyl chloride,98%;2-Thiophenesulfonyl
CAS:16629-19-9
MF:C4H3ClO2S2
MW:182.65
EINECS:240-677-1
Product Categories:Sulphonyl Chlorides;Thiophenes & Benzothiophenes;Thiophene&Benzothiophene;Thiophene intermediates;Heterocycle-oher series;Thiophenes;Heterocyclic Building Blocks;Building Blocks;Thiophenes & Benzothiophenes;Sulphonyl Chlorides
Mol File:16629-19-9.mol
2-Thiophenesulfonyl chloride Structure
2-Thiophenesulfonyl chloride Chemical Properties
Melting point 30-32 °C(lit.)
Boiling point 130-132 °C14 mm Hg(lit.)
density 1.534 (estimate)
refractive index 1.5722-1.5742
Fp >110°C
storage temp. Keep in dark place,Inert atmosphere,2-8°C
solubility soluble in Chloroform, Ethyl Acetate
form solid
color White to Almost white
Water Solubility Reacts with water.
Sensitive Moisture Sensitive
BRN 123536
Stability:Moisture sensitive
InChI1S/C4H3ClO2S2/c5-9(6,7)4-2-1-3-8-4/h1-3H
InChIKeyVNNLHYZDXIBHKZ-UHFFFAOYSA-N
SMILESClS(=O)(=O)c1cccs1
CAS DataBase Reference16629-19-9(CAS DataBase Reference)
NIST Chemistry Reference2-Thiophene sulfonyl chloride(16629-19-9)
EPA Substance Registry System2-Thiophenesulfonyl chloride (16629-19-9)
Safety Information
Hazard Codes C
Risk Statements 34
Safety Statements 26-36/37/39-45-28A-25-27
RIDADR UN 3261 8/PG 2
WGK Germany 3
F 10-21
Hazard Note Corrosive
TSCA TSCA listed
HazardClass 8
PackingGroup II
HS Code 29349990
Storage Class8A - Combustible corrosive hazardous materials
Hazard ClassificationsSkin Corr. 1B
MSDS Information
ProviderLanguage
Thiophene-2-sulfonyl chloride English
SigmaAldrich English
ACROS English
ALFA English
2-Thiophenesulfonyl chloride Usage And Synthesis
Chemical Properties2-Thiophenesulfonyl chloride is colorless to brown low melting solid or liquid
Uses2-Thiophenesulfonyl chloride is a compound used in the preparation of various pharmaceuticals. Thiophene-2-sulfonyl Chloride was used as an intermediate in the synthesis of β-Cell apoptosis supressor .
Uses2-Thiophenesulfonyl chloride has been used in the preparation of 2-((trans-2-phenyl cyclopropyl)sulfonyl)thiophene
Synthesis Reference(s)The Journal of Organic Chemistry, 39, p. 3286, 1974 DOI: 10.1021/jo00936a030
General DescriptionKinetics of reactions of 2-thiophenesulfonyl chloride with substituted anilines in methanol has been reported. Kinetics of solvolysis of 2-thiophenesulfonyl chloride in binary solvent mixtures has been studied.
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