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| | Goserelin EP Impurity L ((D-Leu7)-Goserelin) Basic information |
| Product Name: | Goserelin EP Impurity L ((D-Leu7)-Goserelin) | | Synonyms: | Goserelin EP Impurity L ((D-Leu7)-Goserelin);Goserelin EP Impurity L;Goserelin Impurity 12 （Goserelin EP Impurity L);GoserelinEPImpurityL-Goserelin);GoserelinEPImpurityLDiacetate-GoserelinDiacetate);L-Proline, 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-O-(1,1-dimethylethyl)-D-seryl-D-leucyl-L-arginyl-, 2-(aminocarbonyl)hydrazide;(D-Ser(tBu)?,D-Leu?,Azagly??)-LHRH;800009L | | CAS: | 1926163-38-3 | | MF: | C59H84N18O14 | | MW: | 1269.41 | | EINECS: | | | Product Categories: | | | Mol File: | 1926163-38-3.mol |  |
| | Goserelin EP Impurity L ((D-Leu7)-Goserelin) Chemical Properties |
| density | 1.50±0.1 g/cm3(Predicted) | | pka | 9.82±0.15(Predicted) | | Sequence | {Pyr}-His-Trp-Ser-Tyr-{d-Ser(tBu)}-{d-Leu}-Arg-Pro-{Azagly}-NH2 |
| | Goserelin EP Impurity L ((D-Leu7)-Goserelin) Usage And Synthesis |
| Uses | (D-Ser(tBu)6,D-Leu7,Azagly10)-LHRH is an analogue of luteinizing hormone-releasing hormone (LHRH). LHRH plays a central role in the control of reproduction by stimulating the release of pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH)[1]. | | References | [1] Horvath JE, et al. Effects of long-term treatment with the luteinizing hormone-releasing hormone (LHRH) agonist Decapeptyl and the LHRH antagonist Cetrorelix on the levels of pituitary LHRH receptors and their mRNA expression in rats. Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):15048-53. DOI:10.1073/pnas.232579499 |
| | Goserelin EP Impurity L ((D-Leu7)-Goserelin) Preparation Products And Raw materials |
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