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| | (D-Ser4)-goserelin Basic information |
| Product Name: | (D-Ser4)-goserelin | | Synonyms: | (D-SER4,D-SER(TBU)6,AZAGLY10)-GONADOTROPIN-RELEASING HORMONE;(D-SER4,D-SER(TBU)6,AZAGLY10)-LHRH;(D-SER4,D-SER(TBU)6,AZAGLY10)-LUTEINIZING HORMONE-RELEASING FACTOR;(D-SER4,D-SER(TBU)6,AZAGLY10)-LUTEINIZING HORMONE-RELEASING HORMONE;PYR-HIS-TRP-D-SER-TYR-D-SER(TBU)-LEU-ARG-PRO-AZAGLY-NH2;(D-SER4)-GOSERELIN ; PYR-HIS-TRP-D-SER-TYR-D-SER(TBU)-LEU-ARG-PRO-AZAGLY-NH2;Goserelin Impurity 1 （Goserelin EP Impurity A);L-Proline, 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-D-seryl-L-tyrosyl-O-(1,1-dimethylethyl)-D-seryl-L-leucyl-L-arginyl-, 2-(aminocarbonyl)hydrazide | | CAS: | 1926163-39-4 | | MF: | C59H84N18O14 | | MW: | 1269.41 | | EINECS: | | | Product Categories: | Pepetides;peptides | | Mol File: | Mol File |  |
| | (D-Ser4)-goserelin Chemical Properties |
| density | 1.50±0.1 g/cm3(Predicted) | | storage temp. | -15°C | | pka | 9.82±0.15(Predicted) | | Sequence | {Pyr}-His-Trp-{d-Ser}-Tyr-{d-Ser(tBu)}-Leu-Arg-Pro-{Azagly}-NH2 |
| | (D-Ser4)-goserelin Usage And Synthesis |
| Uses | (D-Ser4,D-Ser(tBu)6,Azagly10)-LHRH is an analogue of luteinizing hormone-releasing hormone (LHRH). LHRH plays a central role in the control of reproduction by stimulating the release of pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH)[1]. | | References | [1] Horvath JE, et al. Effects of long-term treatment with the luteinizing hormone-releasing hormone (LHRH) agonist Decapeptyl and the LHRH antagonist Cetrorelix on the levels of pituitary LHRH receptors and their mRNA expression in rats. Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):15048-53. DOI:10.1073/pnas.232579499 |
| | (D-Ser4)-goserelin Preparation Products And Raw materials |
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