mTOR inhibitor-2

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mTOR inhibitor-2 Suppliers list
Company Name: BOC Sciences  
Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Company Name: Sichuan Wei Keqi Biological Technology Co., Ltd.  
Tel: 028-81700200 18116577057
Email: 3003855609@qq.com
Company Name: Shanghai Beckham Medical Technology Co., Ltd  
Tel: 13816613772
Email: huahero21@sina.com
Company Name: TargetMol Chemicals Inc.  
Tel: +1-781-999-5354; +1-00000000000
Email: marketing@targetmol.com
Company Name: Nantong Hanfang Biotechnology Co. , Ltd.  
Tel: hanfangpharma@126.com 18017580634
Email: hanfangpharma@126.com

mTOR inhibitor-2 manufacturers
mTOR inhibitor-2 Basic information
Product Name:mTOR inhibitor-2
Synonyms:mTOR inhibitor-2;mTOR inhibitor2,mTOR inhibitor 2;1-Piperidineacetonitrile, 4-[9-(6-amino-3-pyridinyl)-2-oxopyrazino[2,3-c]quinolin-1(2H)-yl]-
CAS:2219323-96-1
MF:C23H21N7O
MW:411.46
EINECS:
Product Categories:
Mol File:2219323-96-1.mol
mTOR inhibitor-2 Structure
mTOR inhibitor-2 Chemical Properties
Boiling point 684.2±65.0 °C(Predicted)
density 1.43±0.1 g/cm3(Predicted)
pka5.62±0.26(Predicted)
Safety Information
MSDS Information
mTOR inhibitor-2 Usage And Synthesis
UsesmTOR inhibitor-2 is a highlt potent, selective and oral mTOR inhibitor with an IC50 of 7 nM. mTOR inhibitor-2 inhibits cellular phosphorylation of mTORC1 (pS6 and p4E-BP1) and mTORC2 (pAKT (S473)) substrates[1].
IC 50mTOR: 7 nM (IC50)
References[1] Guo Q, et al. Highly Selective, Potent, and Oral mTOR Inhibitor for Treatment of Cancer as Autophagy Inducer. J Med Chem. 2018 Feb 8;61(3):881-904. DOI:10.1021/acs.jmedchem.7b01402
mTOR inhibitor-2 Preparation Products And Raw materials
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