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| | H-Ala-Ser-Gly-Pro-Leu-Gly-Thr-Leu-Ala-Glu-Glu-Leu-Ser-Ser-Tyr-Ser-Arg-Arg-Lys-Gly-Gly-Phe-Ser-Phe-Arg-Phe-NH2 Basic information |
| Product Name: | H-Ala-Ser-Gly-Pro-Leu-Gly-Thr-Leu-Ala-Glu-Glu-Leu-Ser-Ser-Tyr-Ser-Arg-Arg-Lys-Gly-Gly-Phe-Ser-Phe-Arg-Phe-NH2 | | Synonyms: | ORPHAN GPCR SP9155 AGONIST P550 (MOUSE);ORPHAN G-PROTEIN COUPLED RECEPTOR SP9155 AGONIST PEPTIDE P550 (MOUSE);P550 (MOUSE);Orphan GPCR SP9155 Agonist P550 (Mouse)
Orphan G-Protein Coupled Receptor SP9155 Agonist Peptide P550 (Mouse), P550 (Mouse);Orphan G-Protein Coupled Receptor SP9155 Agonist Peptide P550 (Mouse), P550 (Mouse);Rat 26RFa;Orphan GPCR SP9155 agonist P550 (mouse, rat);L-Phenylalaninamide, L-alanyl-L-serylglycyl-L-prolyl-L-leucylglycyl-L-threonyl-L-leucyl-L-alanyl-L-α-glutamyl-L-α-glutamyl-L-leucyl-L-seryl-L-seryl-L-tyrosyl-L-seryl-L-arginyl-L-arginyl-L-lysylglycylglycyl-L-phenylalanyl-L-seryl-L-phenylalanyl-L-arginyl- | | CAS: | 600171-70-8 | | MF: | C126H195N37O37 | | MW: | 2820.12 | | EINECS: | | | Product Categories: | | | Mol File: | 600171-70-8.mol |  |
| | H-Ala-Ser-Gly-Pro-Leu-Gly-Thr-Leu-Ala-Glu-Glu-Leu-Ser-Ser-Tyr-Ser-Arg-Arg-Lys-Gly-Gly-Phe-Ser-Phe-Arg-Phe-NH2 Chemical Properties |
| density | 1.48±0.1 g/cm3(Predicted) | | Sequence | Ala-Ser-Gly-Pro-Leu-Gly-Thr-Leu-Ala-Glu-Glu-Leu-Ser-Ser-Tyr-Ser-Arg-Arg-Lys-Gly-Gly-Phe-Ser-Phe-Arg-Phe-NH2 |
| | H-Ala-Ser-Gly-Pro-Leu-Gly-Thr-Leu-Ala-Glu-Glu-Leu-Ser-Ser-Tyr-Ser-Arg-Arg-Lys-Gly-Gly-Phe-Ser-Phe-Arg-Phe-NH2 Usage And Synthesis |
| Uses | Orphan GPCR SP9155 agonist P550 (mouse, rat) (26RFa (mouse, rat)), a member of the RFamide peptide family with orexigenic effect, is the cognate ligand of the mouse orphan receptor GPR103, also designated SP9155 or AQ27[1][2]. | | in vivo | 26RFa dose-dependently reduces glucose-induced insulin release, inhibits the insulin responses to both arginine and exendin-4 and did not affect glucagon output in rat pancreas[3]. | | References | [1] Chartrel N, et al. Identification of 26RFa, a hypothalamic neuropeptide of the RFamide peptide family with orexigenic activity. Proc Natl Acad Sci U S A. 2003;100(25):15247-15252. DOI:10.1073/pnas.2434676100
[2] Chartrel N, et al. The Neuropeptide 26RFa (QRFP) and Its Role in the Regulation of Energy Homeostasis: A Mini-Review. Front Neurosci. 2016;10:549. Published 2016 Nov 29. DOI:10.3389/fnins.2016.00549
[3] Egido EM, et al. 26RFa, a novel orexigenic neuropeptide, inhibits insulin secretion in the rat pancreas. Peptides. 2007;28(4):725-730. DOI:10.1016/j.peptides.2006.04.004 |
| | H-Ala-Ser-Gly-Pro-Leu-Gly-Thr-Leu-Ala-Glu-Glu-Leu-Ser-Ser-Tyr-Ser-Arg-Arg-Lys-Gly-Gly-Phe-Ser-Phe-Arg-Phe-NH2 Preparation Products And Raw materials |
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