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THIODIGLYCOLIC ACID

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CAS:505-73-7
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CAS:505-73-7
Company Name: CONIER CHEM AND PHARMA LIMITED
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Products Intro: Product Name:2,2'-dithiodiacetic acid
CAS:505-73-7
Purity:0.99 Package:1kg

THIODIGLYCOLIC ACID manufacturers

  • THIODIGLYCOLIC ACID
  • THIODIGLYCOLIC ACID pictures
  • $1.00 / 1kg
  • 2026-01-30
  • CAS:505-73-7
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 10 mt
  • Dithiodiglycolic acid
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  • $0.00 / 1KG
  • 2022-01-15
  • CAS:505-73-7
  • Min. Order: 1KG
  • Purity: 98.1%
  • Supply Ability: 100 tons
  • THIODIGLYCOLIC ACID
  • THIODIGLYCOLIC ACID pictures
  • $1.00 / 1KG
  • 2020-01-10
  • CAS:505-73-7
  • Min. Order: 1KG
  • Purity: 98% HPLC
  • Supply Ability: 10 tons/month
THIODIGLYCOLIC ACID Basic information
Product Name:THIODIGLYCOLIC ACID
Synonyms:RARECHEM AL BO 1549;SYM-DICARBOXY DIMETHYL DISULFIDE;THIODIACETIC ACID;THIODIGLYCOLLIC ACID;Thioglycolate disulfide;2-{[carboxy(hydroxy)Methyl]sulfanyl}-2-hydroxyacetic acid;2,2'-Disulfanediyldiacetic acid;Dithiodiglycolic acid >=98%
CAS:505-73-7
MF:C4H6O4S2
MW:182.22
EINECS:208-019-8
Product Categories:Pharmaceutical Intermediates
Mol File:505-73-7.mol
THIODIGLYCOLIC ACID Structure
THIODIGLYCOLIC ACID Chemical Properties
Melting point 128-131 °C(lit.)
Boiling point 395.6±27.0 °C(Predicted)
density 1,19 g/cm3
storage temp. -20°C
solubility DMSO (Slightly), Methanol (Slightly)
pkapK1:3.32;pK2:4.29 (25°C)
form Solid
color White to Off-White
Water Solubility very faint turbidity
Cosmetics Ingredients FunctionsREDUCING
InChIInChI=1S/C4H6O4S2/c5-3(6)1-9-10-2-4(7)8/h1-2H2,(H,5,6)(H,7,8)
InChIKeyDLLMHEDYJQACRM-UHFFFAOYSA-N
SMILESS(CC(O)=O)SCC(O)=O
LogP1.390 (est)
CAS DataBase Reference505-73-7(CAS DataBase Reference)
EPA Substance Registry SystemAcetic acid, 2,2'-dithiobis- (505-73-7)
Safety Information
Hazard Codes C,Xi
Risk Statements 34-36/37/38
Safety Statements 26-36/37/39-45-36
RIDADR UN 3261 8/PG 2
WGK Germany 2
RTECS AJ6475000
13
TSCA TSCA listed
HS Code 2930.90.4950
Storage Class11 - Combustible Solids
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
THIODIGLYCOLIC ACID Usage And Synthesis
UsesThiodiglycolic acid is a major metabolite of vinyl chloride monomer and ifosfamide (an anti-cancer drug) in human urine. It is used as an analytical reagent for the detection of copper, lead, mercury and silver.
DefinitionChEBI: Thiodiacetic acid is a dicarboxylic acid.
Synthesis

Dithiol dihydroxyacetic acid was prepared as follows: 120g of 2-mercaptoacetic acid, 500g of ethyl acetate and 0.6g of potassium iodide were mixed homogeneously under the condition of temperature of 20C according to mass to form solution A; 80g of hydrogen peroxide with the concentration of 30wt% was added to solution A slowly and the reaction was kept in a warm state for 2h; at the end of the reaction, the obtained solution was washed by 300mL of saturated sodium sulfite solution. After washing and evaporating ethyl acetate under reduced pressure, dithiol dihydroxyacetic acid was obtained.

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