1-(5-chloro-2-methylphenyl)-3-(2-methylpropyl)thi ourea

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1-(5-chloro-2-methylphenyl)-3-(2-methylpropyl)thi ourea manufacturers

  • HDL376
  • HDL376 pictures
  • $83.00
  • 2026-08-01
  • CAS:147751-31-3
  • Purity: 98.92%
  • Supply Ability: 10g
1-(5-chloro-2-methylphenyl)-3-(2-methylpropyl)thi ourea Basic information
Product Name:1-(5-chloro-2-methylphenyl)-3-(2-methylpropyl)thi ourea
Synonyms:1-(5-chloro-2-methylphenyl)-3-(2-methylpropyl)thi ourea;HDL 376;HDL376;HDL-376;Thiourea, N-(5-chloro-2-methylphenyl)-N'-(2-methylpropyl)-;HDL376, 10 mM in DMSO
CAS:147751-31-3
MF:C12H17ClN2S
MW:256.79
EINECS:
Product Categories:
Mol File:147751-31-3.mol
1-(5-chloro-2-methylphenyl)-3-(2-methylpropyl)thi ourea Structure
1-(5-chloro-2-methylphenyl)-3-(2-methylpropyl)thi ourea Chemical Properties
Boiling point 332.2±52.0 °C(Predicted)
density 1.181±0.06 g/cm3(Predicted)
form Solid
pka12.20±0.70(Predicted)
color White to off-white
Safety Information
MSDS Information
1-(5-chloro-2-methylphenyl)-3-(2-methylpropyl)thi ourea Usage And Synthesis
UsesHDL376 is a scavenger receptor class B type I (SR-BI) inhibitor. HDL376 directly inhibits SR-BI-mediated lipid transport in cells and in liposomes reconstituted with purified SR-BI (IC50 = 0.22 μM). HDL376 can be used for the research of atherosclerotic coronary artery disease[1].
References[1] Nieland TJ, et al. Influence of HDL-cholesterol-elevating drugs on the in vitro activity of the HDL receptor SR-BI. J Lipid Res. 2007 Aug;48(8):1832-45. DOI:10.1194/jlr.M700209-JLR200
1-(5-chloro-2-methylphenyl)-3-(2-methylpropyl)thi ourea Preparation Products And Raw materials
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