D,L-erythro-1-Phenyl-2-decanoylamino-3-morpholino-1-propanol HCl

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D,L-erythro-1-Phenyl-2-decanoylamino-3-morpholino-1-propanol HCl Basic information
Product Name:D,L-erythro-1-Phenyl-2-decanoylamino-3-morpholino-1-propanol HCl
Synonyms:D,L-ERYTHRO-PDMP;Decanamide, N-[(1R,2S)-2-hydroxy-1-(4-morpholinylmethyl)-2-phenylethyl]-, rel-;D,L-erythro-PDMP, glucosylceramide synthase inhibitor isomer;D,L-erythro-1-Phenyl-2-decanoylamino-3-morpholino-1-propanol HCl
CAS:109760-77-2
MF:C23H38N2O3
MW:390.56
EINECS:
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Mol File:109760-77-2.mol
D,L-erythro-1-Phenyl-2-decanoylamino-3-morpholino-1-propanol HCl Structure
D,L-erythro-1-Phenyl-2-decanoylamino-3-morpholino-1-propanol HCl Chemical Properties
Boiling point 586.0±50.0 °C(Predicted)
density 1.047±0.06 g/cm3(Predicted)
pka13.60±0.20(Predicted)
Safety Information
MSDS Information
D,L-erythro-1-Phenyl-2-decanoylamino-3-morpholino-1-propanol HCl Usage And Synthesis
UsesD,L-erythro-PDMP is an erythro isomer of PDMP. D,L-erythro-PDMP causes growth inhibition of cultured rabbit skin fibroblasts. PDMP is an effective inhibitor of UDP-glucose:ceramide glucosyltransferase[1][2].
References[1] Uemura K, et al. Effect of an inhibitor of glucosylceramide synthesis on cultured rabbit skin fibroblasts. J Biochem. 1990 Oct;108(4):525-30. DOI:10.1093/oxfordjournals.jbchem.a123236
[2] Abe A, et al. Induction of glucosylceramide synthase by synthase inhibitors and ceramide. Biochim Biophys Acta. 1996 Feb 16;1299(3):333-41. DOI:10.1016/0005-2760(95)00217-0
D,L-erythro-1-Phenyl-2-decanoylamino-3-morpholino-1-propanol HCl Preparation Products And Raw materials
Tag:D,L-erythro-1-Phenyl-2-decanoylamino-3-morpholino-1-propanol HCl(109760-77-2) Related Product Information
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