tibric acid manufacturers
- Tibric acid
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- $1520.00
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2026-05-11
- CAS:37087-94-8
- Purity:
- Supply Ability: 10g
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| | tibric acid Basic information |
| Product Name: | tibric acid | | Synonyms: | tibric acid;Tibric;2-Chloro-5-[(3α,5α-dimethylpiperidino)sulfonyl]benzoic acid;2-Chloro-5-[[(3R,5S)-3,5-dimethylpiperidino]sulfonyl]benzoic acid;2-Chloro-5-[[(3S,5R)-3,5-dimethylpiperidino]sulfonyl]benzoic acid;CP-18524 | | CAS: | 37087-94-8 | | MF: | C14H18ClNO4S | | MW: | 331.82 | | EINECS: | 2533440 | | Product Categories: | | | Mol File: | 37087-94-8.mol |  |
| | tibric acid Chemical Properties |
| Boiling point | 488.193±55.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.331±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | pka | 2.519±0.25(predicted) | | form | Solid | | color | White to off-white |
| | tibric acid Usage And Synthesis |
| Uses | Tibric acid (CP 18524) has similar effects to those of hypolipidemic agents. Tibric acid has orally active triglyceride-lowering effects. Tibric acid can be used for research of hypertriglyceridemia[1][2]. | | in vivo | Tibric acid (13-125 mg/kg/d, oral administration, daily for 1 week) reduces serum cholesterol and triglyceride levels in rats[2].
| Animal Model: | Rats[1] | | Dosage: | 13, 25, 125 mg/kg/d | | Administration: | oral administration, daily for 1 week | | Result: | Decreased serum cholesterol and triglyceride levels, but increased total liver content of cholesterol, phospholipids, and triglycerides. |
| | References | [1] Bielmann P, et al. Dose-response to tibric acid: a new hypolipidemic drug in type IV hyperlipoproteinemia. Clin Pharmacol Ther. 1975 May;17(5):606-11. DOI:10.1002/cpt1975175606
[2] Cayen MN, et al. Effect of tibric acid on hepatic cholesterol synthesis in rats. Lipids. 1977 Aug;12(8):684-8. DOI:10.1007/BF02533766 |
| | tibric acid Preparation Products And Raw materials |
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