- Sodium Aescinate
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- $68.00
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2026-07-31
- CAS:20977-05-3
- Purity: 95.17%
- Supply Ability: 10g
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| | Escin, monosodium salt Basic information |
| | Escin, monosodium salt Chemical Properties |
| Melting point | 250-252 °C | | solubility | ≥24.5mg/ml in DMSO | | form | Powder | | color | White to off-white |
| | Escin, monosodium salt Usage And Synthesis |
| Description | Escin, monosodium salt is a natural product obtained from the plant horse chestnut. It is used in the treatment of chronic venous insufficiency, where it has been shown to have anti-inflammatory and anti-thrombotic effects. It is a mixture of polysulphated disaccharides that can be purified by HPLC. | | Chemical Properties | Sodium saponin salt obtained from the extract of the dried mature fruit (Solanum serrata) of the Castanea plant. | | Uses | Monosodium salt of Escin (E658790), has been used as a treatment for ischemic damage, hemorrhoids, and trauma or for recovery post-operation. Also used in the treatment of adenocarcinoma cell lines. | | Safety Profile | Poison by ingestion,
intravenous, intraperitoneal, and
subcutaneous routes. Experimental
teratogenic and reproductive effects. When
heated to decomposition it emits toxic
fumes of Na2O. See also SAPONIN and
other escin entries. | | in vivo | Sodium aescinate may effectively controls and improves wound healing in diabetic rats via its anti-inflammatory and antioxidant activities[1].
Sodium aescinate treatment can alleviate the symptom of polycystic ovary syndrome (PCOS) in rat model through regulating the PI3K/Akt/GSK3-β pathway[4].
| | target | NO | TNF-α | IL Receptor | Bcl-2/Bax | VEGFR |
| | Escin, monosodium salt Preparation Products And Raw materials |
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