| Company Name: |
Biolab Reagents |
| Tel: |
027-65279366 18108604356 |
| Email: |
products@biolabreagent.com |
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| Product Name: | uPAR
| | Synonyms: | Anti-PLAUR antibody produced in rabbit;CD87;URKR;PLAUR;Urokinase Plasminogen Activator Receptor ELISA Kit, BioAssay™Recombinant Human CD87/PLAUR Protein, His Tag;uPAR | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![uPAR
Structure]() |
| storage temp. | -20°C | | form | buffered aqueous solution | | biological source | rabbit |
| WGK Germany | WGK 2 | | Storage Class | 12 - Non Combustible Liquids | | Hazard Classifications | Aquatic Chronic 3 Skin Sens. 1 |
| Uses | Suggested starting dilutions are as follows: ICC/IF: 1:100-1:1000, WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. | | Biological Activity | This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions th at have not yet been fully defined. [provided by RefSeq] |
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Preparation Products And Raw materials |
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