Benzamide, N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-4-nitro-

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Company Name: TargetMol Chemicals Inc.
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Products Intro: Product Name:Anti-inflammatory agent 34
CAS:867301-81-3
Purity:98.82% Package:1mg;34USD|5mg;73USD|10mg;118USD
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Products Intro: Product Name:Anti-inflammatory agent 34
CAS:867301-81-3
Purity:98% by HPLC Remarks:Please reach out to us for more information about custom solutions.
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Products Intro: Product Name:WAY-659694
CAS:867301-81-3
Package:1 mg；10 mg；100 mg；200 mg；25 mg；5 mg；50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
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Products Intro: Product Name:N-(4-Methyl-2-oxo-2H-chromen-7-yl)-4-nitrobenzamide
CAS:867301-81-3
Purity:98% Package:$275.9/5mg;$447.9/10mg;$859.9/25mg;$1374.9/50mg;$2404.9/100mg;Bulk package Remarks:98%
Company Name: Shanghai Lollane Biological Technology Co.,Ltd.  
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Products Intro: Product Name:WAY-659694
CAS:867301-81-3
Purity:98% HPLC Package:5mg，10mg，50mg，100mg，1g，5g

Benzamide, N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-4-nitro- manufacturers
Benzamide, N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-4-nitro- Basic information
Product Name:Benzamide, N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-4-nitro-
Synonyms:Benzamide, N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-4-nitro-;WAY-659694;N-(4-Methyl-2-oxo-2H-chromen-7-yl)-4-nitrobenzamide;Anti-inflammatory agent 34;WAY659694,WAY 659694
CAS:867301-81-3
MF:C17H12N2O5
MW:324.29
EINECS:
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Mol File:867301-81-3.mol
Benzamide, N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-4-nitro- Structure
Benzamide, N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-4-nitro- Chemical Properties
Melting point >320 °C(Solv: ethanol (64-17-5))
Boiling point 470.4±45.0 °C(Predicted)
density 1.436±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF : 1.85 mg/mL (5.70 mM; ultrasonic and warming and heat to 60°C)
pka11.05±0.20(Predicted)
form Solid
color Off-white to light yellow
Safety Information
MSDS Information
Benzamide, N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-4-nitro- Usage And Synthesis
UsesAnti-inflammatory agent 34 (Compound IVf) is an orally active anti-inflammatory and analgesic agent[1].
in vivo

Anti-inflammatory agent 34 (Compound IVf) (200mg/kg; p.o.; single dose) shows inhibitory activity on carrageenan induced rat paw edema, and shows analgesic activity in mice[1].

Animal Model:Male albino rats, carrageenan-induced rat paw edema assay model[1]
Dosage:200 mg/kg
Administration:Oral, single dose
Result:Showed 55.7 ± 0.019% inhibition on carrageenan induced rat paw edema at the 3rd h.
Animal Model:Albino mice, acetic acid induced writhing method[1]
Dosage:200 mg/kg
Administration:Oral, single dose
Result:Showed 48.1% analgesic activity.
References[1] Ronad PM, et al. Synthesis and evaluation of anti-inflammatory and analgesic activities of a novel series of substituted-N-(4-methyl-2-oxo-2H-chromen-7-yl) benzamides. Arzneimittelforschung. 2008;58(12):641-6. DOI:10.1055/s-0031-1296565
Benzamide, N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-4-nitro- Preparation Products And Raw materials
Tag:Benzamide, N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-4-nitro-(867301-81-3) Related Product Information
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