N-(2-methoxybenzyl)-5-nitrofuran-2-carboxamide

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N-(2-methoxybenzyl)-5-nitrofuran-2-carboxamide Basic information
Product Name:N-(2-methoxybenzyl)-5-nitrofuran-2-carboxamide
Synonyms:N-(2-methoxybenzyl)-5-nitrofuran-2-carboxamide;2-Furancarboxamide, N-[(2-methoxyphenyl)methyl]-5-nitro-;WAY-638127;Antituberculosis agent-5;WAY 638127,WAY638127
CAS:313981-44-1
MF:C13H12N2O5
MW:276.24
EINECS:
Product Categories:
Mol File:313981-44-1.mol
N-(2-methoxybenzyl)-5-nitrofuran-2-carboxamide Structure
N-(2-methoxybenzyl)-5-nitrofuran-2-carboxamide Chemical Properties
Boiling point 474.6±45.0 °C(Predicted)
density 1.320±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
pka12.48±0.46(Predicted)
form Solid
color Light yellow to yellow
Safety Information
MSDS Information
N-(2-methoxybenzyl)-5-nitrofuran-2-carboxamide Usage And Synthesis
UsesAntituberculosis agent-5 (compound 52) is a nitrofuranylamide derivative, inhibits M. tuberculosis UDP-Gal mutase. Antituberculosis agent-5 inhibits Glf activity with an IC50 value of 99 μM/mL and resists tuberculosis (TB) with a MIC value of 1.6 μg/mL[1].
References[1] Tangallapally RP, et al. Synthesis and evaluation of nitrofuranylamides as novel antituberculosis agents. J Med Chem. 2004 Oct 7;47(21):5276-83. DOI:10.1021/jm049972y
N-(2-methoxybenzyl)-5-nitrofuran-2-carboxamide Preparation Products And Raw materials
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