H-LYS-GLN-ALA-GLY-ASP-VAL-OH

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Products Intro: Product Name:H-LYS-GLN-ALA-GLY-ASP-VAL-OH
CAS:80755-87-9
Purity:99% Package:1KG;7USD
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Products Intro: Product Name:KQAGDV
CAS:80755-87-9
Purity:0.98 Package:1G;10G
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Products Intro: Product Name:H-Lys-Gln-Ala-Gly-Asp-Val-OH
CAS:80755-87-9
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Products Intro: Product Name:H-Lys-Gln-Ala-Gly-Asp-Val-OH
CAS:80755-87-9
Purity:99% Package:5mg;10mg;100mg;1g;10g;100g
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Products Intro: Product Name:KQAGDV
CAS:80755-87-9
Purity:98% HPLC Package:5mg;1G;10G;100G;1KG
H-LYS-GLN-ALA-GLY-ASP-VAL-OH Basic information
Product Name:H-LYS-GLN-ALA-GLY-ASP-VAL-OH
Synonyms:H-LYS-GLN-ALA-GLY-ASP-VAL-OH;KQAGDV;LYS-GLN-ALA-GLY-ASP-VAL;L-Valine, L-lysyl-L-glutaminyl-L-alanylglycyl-L-α-aspartyl-;Fibrinogen γ-chain fragment;Fibrinogen γ-chain fragmen
CAS:80755-87-9
MF:C25H44N8O10
MW:616.66
EINECS:
Product Categories:Other Peptides;Peptides and Proteins;Peptides for Cell Biology
Mol File:80755-87-9.mol
H-LYS-GLN-ALA-GLY-ASP-VAL-OH Structure
H-LYS-GLN-ALA-GLY-ASP-VAL-OH Chemical Properties
storage temp. -20°C
form powder
color white to off-white
SequenceLys-Gln-Ala-Gly-Asp-Val
InChIKeyAFAFFVKJJYBBTC-UHFFFAOYSA-N
SMILESCC(C)C(NC(=O)C(CC(O)=O)NC(=O)CNC(=O)C(C)NC(=O)C(CCC(N)=O)NC(=O)C(N)CCCCN)C(O)=O
Safety Information
WGK Germany 3
Storage Class11 - Combustible Solids
MSDS Information
ProviderLanguage
SigmaAldrich English
H-LYS-GLN-ALA-GLY-ASP-VAL-OH Usage And Synthesis
UsesLys-Gln-Ala-Gly-Asp-Val (KQAGDV) is the six most carboxyl-terminal amino acids in the fibrinogen γ-chain sequence. Lys-Gln-Ala-Gly-Asp-Val is a cell adhesion peptide which is mediated through the α2bβ3 integrin. Lys-Gln-Ala-Gly-Asp-Val is a potent adhesion ligand for smooth muscle cells (SMCs)[1][2].
DefinitionChEBI: Lys-Gln-Ala-Gly-Asp-Val is an oligopeptide.
Biochem/physiol ActionsLys-Gln-Ala-Gly-Asp-Val (KQAGDV) is a cell adhesion peptide used to study adhesion of platelets to neutrophils via the integrin glycoproteins gpIIb/IIIa.
References[1] Dong CL, et al. The cytocompatability of polyhydroxyalkanoates coated with a fusion protein of PHA repressor protein (PhaR) and Lys-Gln-Ala-Gly-Asp-Val (KQAGDV) polypeptide. Biomaterials. 2012 Mar;33(9):2593-9. DOI:10.1016/j.biomaterials.2011.12.020
[2] Mann BK, et al. Tethered-TGF-beta increases extracellular matrix production of vascular smooth muscle cells. Biomaterials. 2001 Mar;22(5):439-44. DOI:10.1016/s0142-9612(00)00196-4
H-LYS-GLN-ALA-GLY-ASP-VAL-OH Preparation Products And Raw materials
Tag:H-LYS-GLN-ALA-GLY-ASP-VAL-OH(80755-87-9) Related Product Information
HIS-HIS-LEU-GLY-GLY-ALA-LYS-GLN-ALA-GLY-ASP-VAL H-ASP-VAL-OH H-LYS-GLN-ALA-GLY-ASP-VAL-OH FIBRINOGEN GAMMA-CHAIN (397-411)