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| | Dexsotalol Basic information |
| Product Name: | Dexsotalol | | Synonyms: | Dexsotalol;(S)-Sotalol;Methanesulfonamide, N-[4-[(1S)-1-hydroxy-2-[(1-methylethyl)amino]ethyl]phenyl]- (9CI);Methanesulfonamide, N-[4-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]phenyl]-, (S)-;N-[4-[(1S)-1-Hydroxy-2-[(1-methylethyl)amino]ethyl]phenyl]methanesulfonamide;Methanesulfonamide, N-[4-[(1S)-1-hydroxy-2-[(1-methylethyl)amino]ethyl]phenyl]-;Dextrosotalol | | CAS: | 30236-32-9 | | MF: | C12H20N2O3S | | MW: | 272.36 | | EINECS: | | | Product Categories: | | | Mol File: | 30236-32-9.mol |  |
| | Dexsotalol Chemical Properties |
| form | Solid | | color | White to off-white |
| | Dexsotalol Usage And Synthesis |
| Uses | Cardiac depressant (anti-arrhythmic). | | in vivo | (+)-Sotalol (8 mg/kg, i.v.) suppresses the induction of ventricular tachyarrhythmias by programmed stimulation in dogs[3].
| Animal Model: | Programmed stimulated Dogs[3] | | Dosage: | 8 mg/kg | | Administration: | Intravenous injection (i.v.) | | Result: | Increased normal zone ventricular refractoriness, and prevented propagation of programmed ventricular extra-stimuli of sufficient prematurity to elicit tachyarrhythmias. |
| | IC 50 | β-adrenoceptor |
| | Dexsotalol Preparation Products And Raw materials |
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