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| | C6NBD-Sphingosine,beta-D-galactosyl Basic information |
| Product Name: | C6NBD-Sphingosine,beta-D-galactosyl | | Synonyms: | C6?NBD-Sphingosine,?beta-D-galactosyl;N-[6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)aMino]hexanoyl]-D-galactosyl-1-1'-sphingosine;N-[6-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]HEXANOYL]-D-GALACTOSYL-1-1'-SPHINGOSINE;C6-NBD GALACTOSYL CERAMIDE;C6 NBD Galactosylceramide (d18:1/6:0);Hexanamide, N-[(1S,2R,3E)-1-[(β-D-galactopyranosyloxy)methyl]-2-hydroxy-3-heptadecen-1-yl]-6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-;C6 NBD-Sphingosine, beta-D-galactosylsphingosine;N-(NBD-Aminocaproyl)sphingosine β-D-galactosyl;N-[6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl]-D-galactosyl-β1-1'-sphingosine | | CAS: | 170212-26-7 | | MF: | C36H59N5O11 | | MW: | 737.88 | | EINECS: | | | Product Categories: | | | Mol File: | 170212-26-7.mol |  |
| | C6NBD-Sphingosine,beta-D-galactosyl Chemical Properties |
| density | 1.27±0.1 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | Chloroform:Methanol (5:1): soluble; Methanol: soluble | | form | A solid | | pka | 12.92±0.70(Predicted) | | Appearance | Solid Powder | | InChIKey | ZYEQNDHFYIPTAY-LFUFHFQKSA-N | | SMILES | [N+](=O)([O-])c1c2n[o]nc2c(cc1)NCCCCCC(=O)N[C@H]([C@H](O)\C=C\CCCCCCCCCCCCC)CO[C@@H]3O[C@@H]([C@@H]([C@@H]([C@H]3O)O)O)CO |
| Storage Class | 11 - Combustible Solids |
| | C6NBD-Sphingosine,beta-D-galactosyl Usage And Synthesis |
| Description | C6 NBD galactosylceramide is a galactosylceramide derivative that is tagged with a fluorescent group C6 nitrobenzoxadiazole (C6 NBD). C6 NBD galactosylceramide has been used to study intracellular localization and metabolism of galactosylceramide, which is a marker of Krabbe disease. | | Uses | C6-NBD Galactosyl Ceramide is suitable for use as a substrate in neutral β-glycosylceramidase (GCase) activity assay. | | Biological Activity | Galactosyl ceramide is also known as galactocerebroside and is produced in the lumen of the endoplasmic reticulum. Galactosyl ceramide is a vaccine adjuvant, it stimulates natural killer T (NKT) cells to increase secretion of T helper type 1 (Th1) and T-helper type 2 (TH2) cytokines. Galactosyl ceramide accumulation in excess is responsible for diseases such as Krabbeμs disease. Galactocerebroside is a precursor of 3μ-sulfo-galactosylceramide, a vital sulfoglycolipid found in the brain and other organs. |
| | C6NBD-Sphingosine,beta-D-galactosyl Preparation Products And Raw materials |
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