Ethanesulfonamide, N-[(3aR,4R,5R,7R,7aS)-2-[4-cyano-3-(trifluoromethyl)phenyl]octahydro-4,7-dimethyl-1,3-dioxo-4,7-epoxy-1H-isoindol-5-yl]- manufacturers
- BMS-641988
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- $163.00
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2026-07-27
- CAS:1093276-09-5
- Purity: 99.57%
- Supply Ability: 10g
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| | Ethanesulfonamide, N-[(3aR,4R,5R,7R,7aS)-2-[4-cyano-3-(trifluoromethyl)phenyl]octahydro-4,7-dimethyl-1,3-dioxo-4,7-epoxy-1H-isoindol-5-yl]- Basic information |
| Product Name: | Ethanesulfonamide, N-[(3aR,4R,5R,7R,7aS)-2-[4-cyano-3-(trifluoromethyl)phenyl]octahydro-4,7-dimethyl-1,3-dioxo-4,7-epoxy-1H-isoindol-5-yl]- | | Synonyms: | Ethanesulfonamide, N-[(3aR,4R,5R,7R,7aS)-2-[4-cyano-3-(trifluoromethyl)phenyl]octahydro-4,7-dimethyl-1,3-dioxo-4,7-epoxy-1H-isoindol-5-yl]- | | CAS: | 1093276-09-5 | | MF: | C20H20F3N3O5S | | MW: | 471.45 | | EINECS: | | | Product Categories: | | | Mol File: | 1093276-09-5.mol | ![Ethanesulfonamide, N-[(3aR,4R,5R,7R,7aS)-2-[4-cyano-3-(trifluoromethyl)phenyl]octahydro-4,7-dimethyl-1,3-dioxo-4,7-epoxy-1H-isoindol-5-yl]- Structure](CAS/20210305/GIF/1093276-09-5.gif) |
| | Ethanesulfonamide, N-[(3aR,4R,5R,7R,7aS)-2-[4-cyano-3-(trifluoromethyl)phenyl]octahydro-4,7-dimethyl-1,3-dioxo-4,7-epoxy-1H-isoindol-5-yl]- Chemical Properties |
| Boiling point | 678.9±65.0 °C(Predicted) | | density | 1.53±0.1 g/cm3(Predicted) | | pka | 10.06±0.60(Predicted) | | form | Solid | | color | White to light yellow |
| | Ethanesulfonamide, N-[(3aR,4R,5R,7R,7aS)-2-[4-cyano-3-(trifluoromethyl)phenyl]octahydro-4,7-dimethyl-1,3-dioxo-4,7-epoxy-1H-isoindol-5-yl]- Usage And Synthesis |
| Uses | BMS-641988 (compound 23) is an oral active nonsteroidal androgen receptor antagonist with the Ki of 1.7 nM. BMS-641988 shows anticancer activity[1]. | | Definition | ChEBI: N-[(3aR,4R,5R,7R,7aS)-2-[4-cyano-3-(trifluoromethyl)phenyl]-4,7-dimethyl-1,3-dioxo-3a,5,6,7a-tetrahydro-octahydro-1H-4,7-epoxyisoindol-5-yl]ethanesulfonamide is an organonitrogen compound and an organooxygen compound. It is functionally related to a delta-amino acid. | | References | [1] Balog A, et al. Discovery of BMS-641988, a Novel Androgen Receptor Antagonist for the Treatment of Prostate Cancer. ACS Med Chem Lett. 2015;6(8):908-912. Published 2015 Jun 19. DOI:10.1021/acsmedchemlett.5b00173 |
| | Ethanesulfonamide, N-[(3aR,4R,5R,7R,7aS)-2-[4-cyano-3-(trifluoromethyl)phenyl]octahydro-4,7-dimethyl-1,3-dioxo-4,7-epoxy-1H-isoindol-5-yl]- Preparation Products And Raw materials |
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