2-Furanmethanamine, 5-(2-chlorophenyl)-N-[[3-(1-pyrrolidinyl)-3-oxetanyl]methyl]- manufacturers
- FTO-IN-8
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- $119.00
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2026-05-11
- CAS:2640366-38-5
- Purity:
- Supply Ability: 10g
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| | 2-Furanmethanamine, 5-(2-chlorophenyl)-N-[[3-(1-pyrrolidinyl)-3-oxetanyl]methyl]- Basic information |
| | 2-Furanmethanamine, 5-(2-chlorophenyl)-N-[[3-(1-pyrrolidinyl)-3-oxetanyl]methyl]- Chemical Properties |
| Boiling point | 444.4±40.0 °C(Predicted) | | density | 1.234±0.06 g/cm3(Predicted) | | pka | 8.57±0.20(Predicted) | | form | Oil | | color | Light yellow to yellow |
| | 2-Furanmethanamine, 5-(2-chlorophenyl)-N-[[3-(1-pyrrolidinyl)-3-oxetanyl]methyl]- Usage And Synthesis |
| Uses | FTO-IN-8 (FTO-43) is a N6-methyladenosine demethylase (FTO) (fat mass- and obesity-associated protein) inhibitor with the IC50 value of 5.5 μM. FTO-IN-8 has anti-cancer cell proliferative activity[1]. | | References | [1] Sarah Huff, et al. Rational Design and Optimization of m6A-RNA Demethylase FTO Inhibitors as Anticancer Agents. J Med Chem. 2022 Aug 8. DOI:10.1021/acs.jmedchem.1c02075 |
| | 2-Furanmethanamine, 5-(2-chlorophenyl)-N-[[3-(1-pyrrolidinyl)-3-oxetanyl]methyl]- Preparation Products And Raw materials |
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