β-Alanine, N-[3-(dimethylamino)propyl]-N-[3-[2-(dodecyldithio)ethoxy]-3-oxopropyl]-, 2-(dodecyldithio)ethyl ester

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β-Alanine, N-[3-(dimethylamino)propyl]-N-[3-[2-(dodecyldithio)ethoxy]-3-oxopropyl]-, 2-(dodecyldithio)ethyl ester Basic information
Product Name:β-Alanine, N-[3-(dimethylamino)propyl]-N-[3-[2-(dodecyldithio)ethoxy]-3-oxopropyl]-, 2-(dodecyldithio)ethyl ester
Synonyms:β-Alanine, N-[3-(dimethylamino)propyl]-N-[3-[2-(dodecyldithio)ethoxy]-3-oxopropyl]-, 2-(dodecyldithio)ethyl ester;80-O16B;Bis(2-(dodecyldisulfaneyl)ethyl) 3,3'-((3-(dimethylamino)propyl)azanediyl)dipropionate;Bis(2-(dodecyldisulfaneyl)ethyl) 3,3'-((3-(dimethylamino)propyl)azanediyl)dipropionate
CAS:1624618-02-5
MF:C39H78N2O4S4
MW:767.3
EINECS:
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Mol File:1624618-02-5.mol
β-Alanine, N-[3-(dimethylamino)propyl]-N-[3-[2-(dodecyldithio)ethoxy]-3-oxopropyl]-, 2-(dodecyldithio)ethyl ester Structure
β-Alanine, N-[3-(dimethylamino)propyl]-N-[3-[2-(dodecyldithio)ethoxy]-3-oxopropyl]-, 2-(dodecyldithio)ethyl ester Chemical Properties
Boiling point 760.7±60.0 °C(Predicted)
density 1.023±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Ethanol: 10 mg/ml
pka9.49±0.28(Predicted)
form Liquid
color Colorless to light yellow
Safety Information
MSDS Information
β-Alanine, N-[3-(dimethylamino)propyl]-N-[3-[2-(dodecyldithio)ethoxy]-3-oxopropyl]-, 2-(dodecyldithio)ethyl ester Usage And Synthesis
Uses80-O16B is an ionizable cationic lipid containing disulfide bonds that can be used to prepare lipid nanoparticles (LNP)[1].
References[1] Li Y , et al. Intracellular delivery and biodistribution study of CRISPR/Cas9 ribonucleoprotein loaded bioreducible lipidoid nanoparticles. Biomater Sci. 2019 Jan 29;7(2):596-606. DOI:10.1039/c8bm00637g
β-Alanine, N-[3-(dimethylamino)propyl]-N-[3-[2-(dodecyldithio)ethoxy]-3-oxopropyl]-, 2-(dodecyldithio)ethyl ester Preparation Products And Raw materials
Tag:β-Alanine, N-[3-(dimethylamino)propyl]-N-[3-[2-(dodecyldithio)ethoxy]-3-oxopropyl]-, 2-(dodecyldithio)ethyl ester(1624618-02-5) Related Product Information
16-Oxa-19,20-dithia-4,8,12-triazaoctacosanoic acid, 8-methyl-4,12-bis[3-[2-(octyldithio)ethoxy]-3-oxopropyl]-15-oxo-, 2-(octyldithio)ethyl ester 14-Oxa-17,18-dithia-4,7,10-triazatriacontanoic acid, 4,10-bis[3-[2-(dodecyldithio)ethoxy]-3-oxopropyl]-7-methyl-13-oxo-, 2-(dodecyldithio)ethyl ester Tetrakis(2-(octyldisulfaneyl)ethyl) 3,3',3'',3'''-(((methylazanediyl)bis(ethane-2,1-diyl))bis(azanetriyl))tetrapropionate 4A3-SC8 N,N-Di-(beta-carboethoxyethyl)methylamine ethyl 4-[(3-ethoxy-3-oxopropyl)(methyl)amino]butanoate