3-Quinolinecarboxamide, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-N-[4-[[[2-(1-piperidinyl)ethyl]amino]carbonyl]phenyl]-

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3-Quinolinecarboxamide, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-N-[4-[[[2-(1-piperidinyl)ethyl]amino]carbonyl]phenyl]- Suppliers list
Company Name: Guangzhou Younan Technology Co., Ltd  
Tel: 020-82000279 18988941452
Email: YN_research@163.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
3-Quinolinecarboxamide, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-N-[4-[[[2-(1-piperidinyl)ethyl]amino]carbonyl]phenyl]- Basic information
Product Name:3-Quinolinecarboxamide, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-N-[4-[[[2-(1-piperidinyl)ethyl]amino]carbonyl]phenyl]-
Synonyms:3-Quinolinecarboxamide, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-N-[4-[[[2-(1-piperidinyl)ethyl]amino]carbonyl]phenyl]-
CAS:2848720-31-8
MF:C30H37FN6O3
MW:548.65
EINECS:
Product Categories:
Mol File:2848720-31-8.mol
3-Quinolinecarboxamide, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-N-[4-[[[2-(1-piperidinyl)ethyl]amino]carbonyl]phenyl]- Structure
3-Quinolinecarboxamide, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-N-[4-[[[2-(1-piperidinyl)ethyl]amino]carbonyl]phenyl]- Chemical Properties
Boiling point 818.4±65.0 °C(Predicted)
density 1.263±0.06 g/cm3(Predicted)
form Solid
pka11.17±0.70(Predicted)
color White to off-white
Safety Information
MSDS Information
3-Quinolinecarboxamide, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-N-[4-[[[2-(1-piperidinyl)ethyl]amino]carbonyl]phenyl]- Usage And Synthesis
UsesmicroRNA-21-IN-1 (compound A7) is an efficient microRNA inhibitor. microRNA-21-IN-1 has antiproliferative activity against Hela and HCT-116 cells with IC50s of 5.5 μM and 2.8 μM respectively, as well as promotes apoptosis of Hela cells. microRNA-21-IN-1 upregulates the expression of microRNA-21 downstream functional targets (PTEN, EGR1 and SLIT2). microRNA-21-IN-1 can be used for researching anticancer[1].
References[1] Xi XX, et al. Identification of benzamides derivatives of norfloxacin as promising microRNA-21 inhibitors via repressing its transcription. Bioorg Med Chem. 2022;66:116803. DOI:10.1016/j.bmc.2022.116803
3-Quinolinecarboxamide, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-N-[4-[[[2-(1-piperidinyl)ethyl]amino]carbonyl]phenyl]- Preparation Products And Raw materials
Tag:3-Quinolinecarboxamide, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-N-[4-[[[2-(1-piperidinyl)ethyl]amino]carbonyl]phenyl]-(2848720-31-8) Related Product Information
1-ethyl-6-fluoro-3-formyl-1,4-dihydro-4-oxo-7-piperazinylquinoline 3-Quinolinecarboxamide, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-N-[4-[[[2-(1-piperidinyl)ethyl]amino]carbonyl]phenyl]- 7-(4-acetylpiperazin-1-yl)-1-ethyl-6-fluoro-N-(2-hydroxyphenyl)-4-oxoquinoline-3-carboxamide 1-Effmpq 1-Cffopq Piperazine, 1-[(8-fluoro-4-hydroxy-3-quinolinyl)carbonyl]- (9CI)