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| | sampangine Basic information |
| | sampangine Chemical Properties |
| Melting point | 220-222 °C | | Boiling point | 498.2±25.0 °C(Predicted) | | density | 1.404±0.06 g/cm3(Predicted) | | pka | 1.30±0.20(Predicted) |
| | sampangine Usage And Synthesis |
| Uses | Sampangine is an alkaloid that induces apoptosis by inducing cell cycle arrest in the G0/G1 phase. Sampangine can inhibit the biosynthesis of heme[1][2]. | | Definition | ChEBI: Sampangine is a copyrine alkaloid with formula C15H8N2O, extracted from several plants including the stem bark of Cananga odorata. It is a heme biosynthesis inhibitor and exhibits antifungal and anticancer properties. It has a role as a plant metabolite and an antifungal agent. It is an alkaloid and an organic heterotetracyclic compound. | | References | [1] Pérez EG, et al. Alkaloids from the genus Duguetia. Alkaloids Chem Biol. 2010;68:83-156. DOI:10.1016/s1099-4831(10)06803-3
[2] Huang Z, et al. Sampangine inhibits heme biosynthesis in both yeast and human. Eukaryot Cell. 2011 Nov;10(11):1536-44. DOI:10.1128/EC.05170-11 |
| | sampangine Preparation Products And Raw materials |
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