| Company Name: |
BOC Sciences |
| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
LY 302148 manufacturers
- LY 302148
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- $1980.00
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2026-05-11
- CAS:182564-47-2
- Purity:
- Supply Ability: 10g
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| | LY 302148 Basic information |
| Product Name: | LY 302148 | | Synonyms: | LY 302148;1H-Indole, 5-fluoro-3-[1-[2-(1-methyl-1H-pyrazol-4-yl)ethyl]-4-piperidinyl]- | | CAS: | 182564-47-2 | | MF: | C19H23FN4 | | MW: | 326.41 | | EINECS: | | | Product Categories: | | | Mol File: | 182564-47-2.mol |  |
| | LY 302148 Chemical Properties |
| Boiling point | 511.8±50.0 °C(Predicted) | | density | 1.26±0.1 g/cm3(Predicted) | | pka | 16.23±0.30(Predicted) |
| | LY 302148 Usage And Synthesis |
| Description | LY 302148 is a 5-HT1F receptor agonist that inhibits neurogenic dural inflammation in guinea pigs. LY 302148 has potential for migraine therapeutics. | | Uses | LY302148 is a receptor ligand for 5-HT1F. Compared to the Emax of 5-HT, LY302148 behaves as a partial agonist for the 5-HT1F receptor. In the [35S]GTPγS binding assay targeting human 5-HT1F receptors, LY302148 exhibits good potency with an EC50 value of 5.23 nM. LY302148 can be used in the research of migraine[1]. | | References | [1] Wainscott D B, et al. Human 5-HT1F receptor-stimulated [35S] GTPγS binding: correlation with inhibition of guinea pig dural plasma protein extravasation[J]. European journal of pharmacology, 1998, 352(1): 117-124. DOI:10.1016/s0014-2999(98)00336-7 |
| | LY 302148 Preparation Products And Raw materials |
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