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DL-4-Chlorophenylalanine methyl ester hydrochloride

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DL-4-Chlorophenylalanine methyl ester hydrochloride Basic information
Product Name:DL-4-Chlorophenylalanine methyl ester hydrochloride
Synonyms:DL-P-CHLOROPHENYLALANINE METHYL ESTER*HY;4-Chloro-Dl-PhenylalanineMethylEster;4-CHLORO-DL-PHENYLALANINE METHYLESTER HCI;H-p-Chloro-DL-Phe-OMe;2-AMino-3-(4-chloro-phenyl)-propionic acid Methyl ester hydrochloride;(RS)-2-AMino-3-(4-chloro-phenyl)-propionic acid Methyl ester · HCl, H-4-Chloro-DL-Phe-OMe · HCl;(±)-4-Chlorophenylalanine methyl;4-Chloro-DL-phenylalanine methyl
CAS:14173-40-1
MF:C10H13Cl2NO2
MW:250.12
EINECS:238-024-0
Product Categories:Phenylalanine [Phe, F];Unusual Amino Acids;Amino hydrochloride;Tryptophan Hydroxylase;Enzyme Inhibitors;Neurotransmitter Metabolism
Mol File:14173-40-1.mol
DL-4-Chlorophenylalanine methyl ester hydrochloride Structure
DL-4-Chlorophenylalanine methyl ester hydrochloride Chemical Properties
Melting point 186-189 °C(lit.)
storage temp. -20°C
solubility Soluble to 100 mM in water and to 100 mM in DMSO
form Solid
color White to off-white
InChI1S/C10H12ClNO2.ClH/c1-14-10(13)9(12)6-7-2-4-8(11)5-3-7;/h2-5,9H,6,12H2,1H3;1H
InChIKeyGCBCWTWQAFLKJG-UHFFFAOYSA-N
SMILESCl.COC(=O)C(N)Cc1ccc(Cl)cc1
CAS DataBase Reference14173-40-1(CAS DataBase Reference)
Safety Information
Safety Statements 24/25
WGK Germany 3
RTECS AY4452100
HS Code 29224999
Storage Class11 - Combustible Solids
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
DL-4-Chlorophenylalanine methyl ester hydrochloride Usage And Synthesis
Chemical Propertieswhite to off-white powder
Uses4-Chloro-DL-phenylalanine methyl ester hydrochloride has been used to induce 5-hydroxytryptamine (5-HT) depletion in rats.
General Description4-Chloro-DL-phenylalanine methyl ester hydrochloride stimulates glucose intolerance in pregnant mice. Studies have shown that 4-Chloro-DL-phenylalanine methyl ester hydrochloride is associated with cognitive defects in rodents.
Biochem/physiol ActionsTryptophan hydroxylase inhibitor. Crosses blood brain barrier better than pchlorophenylalanine.
storageStore at -20°C
DL-4-Chlorophenylalanine methyl ester hydrochloride Preparation Products And Raw materials
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