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3B Pharmachem (Wuhan) International Co.,Ltd.
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Product Name:Conantokin-T
CAS:127476-26-0
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| Company Name: |
Creative Peptides
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Product Name:Conantokin-T
CAS:127476-26-0
Purity:>98% Package:1g; 10g;100g;1kg Remarks:Peptide Inhibitors
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| Company Name: |
BOC Sciences
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| Products Intro: |
Product Name:Conantokin-T
CAS:127476-26-0
Remarks:Conantokin-T is a non-competitive NMDA receptor antagonist with IC50 value of 0.4 μM. It inhibits Ca2+ influx and glutamate-induced toxicity in central nervous system neurons. It has age-dependent phy
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MedBioPharmaceutical Technology Inc
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| Products Intro: |
Product Name:conantokin-T
CAS:127476-26-0
Purity:98% Package:500ug Remarks:Medbio
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| | conantokin-T Basic information |
| Product Name: | conantokin-T | | Synonyms: | Conatokin t;L-Alaninamide, glycyl-L-α-glutamyl-4-carboxy-L-α-glutamyl-4-carboxy-L-α-glutamyl-L-tyrosyl-L-glutaminyl-L-lysyl-L-methionyl-L-leucyl-4-carboxy-L-α-glutamyl-L-asparaginyl-L-leucyl-L-arginyl-4-carboxy-L-α-glutamyl-L-alanyl-L-α-glutamyl-L-valyl-L-lysyl-L-lysyl-L-asparaginyl- | | CAS: | 127476-26-0 | | MF: | C110H175N31O45S | | MW: | 2683.83 | | EINECS: | | | Product Categories: | | | Mol File: | 127476-26-0.mol |  |
| | conantokin-T Chemical Properties |
| density | 1.57±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | form | Powder |
| | conantokin-T Usage And Synthesis |
| Description | Non-competitive NMDA receptor antagonist (IC50= 0.4μM). Inhibits Ca2+influx and glutamate-induced toxicity in central nervous system neurons. Exhibits age-dependent physiological effects; induces a sleep-like state in young mice and hyperactivity in older mice. | | Uses | Conantokin-T is a γ-carboxyglutamate-containing, N-methyl-D-aspartate (NMDA) antagonist peptidewith an IC50 value of 2 μM. Conantokin-T inhibits NMDA receptor-mediated calcium influx in central nervous system neurons. Conantokin-T can be purified from the venom of the fish-hunting cone snail, Conus tulipa[1]. | | in vivo | Conantokin-T induces sleep-like symptoms in young mice[1]. | | References | [1] J A Haack, et al. Conantokin-T. A gamma-carboxyglutamate containing peptide with N-methyl-d-aspartate antagonist activity. J Biol Chem. 1990 Apr 15;265(11):6025-9. PMID:2180939 |
| | conantokin-T Preparation Products And Raw materials |
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