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| | 2-Oxazolecarboxamide, N-[(3R,5R)-1-cyano-5-methyl-3-pyrrolidinyl]-5-(3-cyanophenyl)- Basic information |
| | 2-Oxazolecarboxamide, N-[(3R,5R)-1-cyano-5-methyl-3-pyrrolidinyl]-5-(3-cyanophenyl)- Chemical Properties |
| density | 1.36±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | | pka | 8.38±0.40(Predicted) |
| | 2-Oxazolecarboxamide, N-[(3R,5R)-1-cyano-5-methyl-3-pyrrolidinyl]-5-(3-cyanophenyl)- Usage And Synthesis |
| Uses | USP30-I-1 is a selective inhibitor of USP30 with an IC50 value of 94 nM. USP30-I-1 can be used in the research of diseases with impaired mitophagy by targeting USP30[1]. | | References | [1] O'Brien D P, et al. Structural Dynamics of the Ubiquitin Specific Protease USP30 in Complex with a Cyanopyrrolidine-Containing Covalent Inhibitor[J]. bioRxiv, 2024: 2024.07. 20.604388. |
| | 2-Oxazolecarboxamide, N-[(3R,5R)-1-cyano-5-methyl-3-pyrrolidinyl]-5-(3-cyanophenyl)- Preparation Products And Raw materials |
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