2-Octyldecyl 6-[[4-(decyloxy)-4-oxobutyl](2-hydroxyethyl)amino]hexanoate

Request For Quotation
2-Octyldecyl 6-[[4-(decyloxy)-4-oxobutyl](2-hydroxyethyl)amino]hexanoate Suppliers list
Company Name: SuZhou Medinoah Co.,LTD.  
Tel: 0512-69561983 13914027025
Email: zhang_q@medinoah.com
Company Name: DC Chemicals  
Tel: 021-58447131 13564518121
Email: doncunbiosci@gmail.com
Company Name: Bide Pharmatech Ltd.  
Tel: 400-1647117 13681763483
Email: product02@bidepharm.com
Company Name: Abosyn  
Tel: 0512-69561983 13914027025
Email: he_qf@medinoah.com
Company Name: Shanghai Yifei Biotechnology Co. , Ltd.  
Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
2-Octyldecyl 6-[[4-(decyloxy)-4-oxobutyl](2-hydroxyethyl)amino]hexanoate Basic information
Product Name:2-Octyldecyl 6-[[4-(decyloxy)-4-oxobutyl](2-hydroxyethyl)amino]hexanoate
Synonyms:2-Octyldecyl 6-[[4-(decyloxy)-4-oxobutyl](2-hydroxyethyl)amino]hexanoate;YK009;decyl 4-(1-hydroxy-12-octyl-9-oxo-3-aza-10-oxaicos-3-yl)butanoate
CAS:2761458-86-8
MF:C40H79NO5
MW:654.06
EINECS:
Product Categories:
Mol File:2761458-86-8.mol
2-Octyldecyl 6-[[4-(decyloxy)-4-oxobutyl](2-hydroxyethyl)amino]hexanoate Structure
2-Octyldecyl 6-[[4-(decyloxy)-4-oxobutyl](2-hydroxyethyl)amino]hexanoate Chemical Properties
Boiling point 687.4±45.0 °C(Predicted)
density 0.933±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)
solubility Ethanol: 5 mg/ml
pka14.75±0.10(Predicted)
Safety Information
MSDS Information
2-Octyldecyl 6-[[4-(decyloxy)-4-oxobutyl](2-hydroxyethyl)amino]hexanoate Usage And Synthesis
DescriptionYK-009 is an ionizable cationic lipid (pKa = 6.512) that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs).1 Administration of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant mRNA in YK-009-containing LNPs induces the production of IgG that binds to the SARS-CoV-2 receptor-binding domain (RBD) in mice, with a boost in IgG titers 10 days after a second dose.WARNING This product is not for human or veterinary use.
References[1] JINRONG LONG. Novel Ionizable Lipid Nanoparticles for SARS-CoV-2 Omicron mRNA Delivery[J]. Advanced Healthcare Materials, 2023, 12 13. DOI: 10.1002/adhm.202202590
2-Octyldecyl 6-[[4-(decyloxy)-4-oxobutyl](2-hydroxyethyl)amino]hexanoate Preparation Products And Raw materials
Tag:2-Octyldecyl 6-[[4-(decyloxy)-4-oxobutyl](2-hydroxyethyl)amino]hexanoate(2761458-86-8) Related Product Information
31hP Octanoic acid, 8-[(2-hydroxyethyl)[6-oxo-6-(undecyloxy)hexyl]amino]-, 1-octylnonyl ester Lipid 331 ALC-0315