Octanoic acid, 8-[(2-hydroxyethyl)[6-oxo-6-(undecyloxy)hexyl]amino]-, 1-octylnonyl ester manufacturers
- SM-102
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- $300.00
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2026-08-03
- CAS:2089251-47-6
- Min. Order: 1G
- Purity: 99%HPLC
- Supply Ability: 5000 G
- SM-102（HUO）
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2026-07-24
- CAS:2089251-47-6
- Min. Order: 1g
- Purity: 98%
- Supply Ability: 1g/bottle , 10g/bottle, 100g/bottle
- SM-102
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- $40.00
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2026-06-01
- CAS:2089251-47-6
- Purity: 98.43%
- Supply Ability: 10g
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| | Octanoic acid, 8-[(2-hydroxyethyl)[6-oxo-6-(undecyloxy)hexyl]amino]-, 1-octylnonyl ester Basic information |
| Product Name: | Octanoic acid, 8-[(2-hydroxyethyl)[6-oxo-6-(undecyloxy)hexyl]amino]-, 1-octylnonyl ester | | Synonyms: | Octanoic acid, 8-[(2-hydroxyethyl)[6-oxo-6-(undecyloxy)hexyl]amino]-, 1-octylnonyl ester;(heptadecan-9-yl 8-((2-hydroxyethyl)(6-oxO-6-(undecyloxy) hexyl) amino) octanoate),;Unii-T7obq65G2I;heptadecan-9-yl 8-[2-hydroxyethyl-(6-oxo-6-undecoxyhexyl)amino]octanoate;Heptadecan-9-yl 8-((2-hydroxyethyl) (6-oxo-6-(undecyloxy) hexyl) amino) octanoate) (SM-102);delivery,SM-102,mRNA,vaccines,SM102,lipid nanoparticle,Inhibitor,SM 102,COVID-19,inhibit;8-[(2-hydroxyethyl)[6-oxo-6-(undecyloxy)hexyl]amino]-octanoic acid, 1-octylnonyl ester;SM-102(HUO) | | CAS: | 2089251-47-6 | | MF: | C44H87NO5 | | MW: | 710.17 | | EINECS: | 610-261-8 | | Product Categories: | Intermediates | | Mol File: | 2089251-47-6.mol | ![Octanoic acid, 8-[(2-hydroxyethyl)[6-oxo-6-(undecyloxy)hexyl]amino]-, 1-octylnonyl ester Structure](CAS/20200611/GIF/2089251-47-6.gif) |
| | Octanoic acid, 8-[(2-hydroxyethyl)[6-oxo-6-(undecyloxy)hexyl]amino]-, 1-octylnonyl ester Chemical Properties |
| Boiling point | 725.8±50.0 °C(Predicted) | | density | 0.925±0.06 g/cm3(Predicted) | | storage temp. | Storage temp. 2-8°C | | solubility | Soluble in Ethanol, DMSO, DMF | | pka | 14.67±0.10(Predicted) | | form | Liquid | | color | Colorless to light yellow | | InChIKey | BGNVBNJYBVCBJH-UHFFFAOYSA-N | | SMILES | C(OC(CCCCCCCC)CCCCCCCC)(=O)CCCCCCCN(CCO)CCCCCC(=O)OCCCCCCCCCCC |
| | Octanoic acid, 8-[(2-hydroxyethyl)[6-oxo-6-(undecyloxy)hexyl]amino]-, 1-octylnonyl ester Usage And Synthesis |
| Description | SM-102, Heptadecan-9-yl 8-{(2-hydroxyethyl)[6-oxo-6-(undecyloxy)hexyl]amino}octanoate equivalent, is a ionizable cationic lipid used with other lipids to form lipid nanoparticles (LNP) in drug delivery. | | Uses | SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines[1][2]. | | References | [1] Staci Sabnis, et al. A Novel Amino Lipid Series for mRNA Delivery: Improved Endosomal Escape and Sustained Pharmacology and Safety in Non-human Primates. Mol Ther. 2018 Jun 6;26(6):1509-1519. DOI:10.1016/j.ymthe.2018.03.010
[2] Escalona-Rayo O, et al. In vitro and in vivo evaluation of clinically-approved ionizable cationic lipids shows divergent results between mRNA transfection and vaccine efficacy. Biomed Pharmacother. 2023 Sep;165:115065. DOI:10.1016/j.biopha.2023.115065
[3] Cho HY, et al. Effective Perturbations on the Amplitude and Hysteresis of Erg-Mediated Potassium Current Caused by 1-Octylnonyl 8-[(2-hydroxyethyl)[6-oxo-6(undecyloxy)hexyl]amino]-octanoate (SM-102), a Cationic Lipid. Biomedicines. 2021 Oct 1;9(10):1367. DOI:10.3390/biomedicines9101367 |
| | Octanoic acid, 8-[(2-hydroxyethyl)[6-oxo-6-(undecyloxy)hexyl]amino]-, 1-octylnonyl ester Preparation Products And Raw materials |
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