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BOC Sciences |
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1-631-485-4226; 16314854226 |
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LY 43578 manufacturers
- LY 43578
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- $32.00
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2026-08-08
- CAS:26766-35-8
- Purity: 99.88%
- Supply Ability: 10g
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| | LY 43578 Basic information |
| Product Name: | LY 43578 | | Synonyms: | LY 43578;Bis(4-chlorophenyl)(pyrimidine-5-yl)methanol;α,α-Bis(4-chlorophenyl)pyrimidine-5-methanol;5-Pyrimidinemethanol, α,α-bis(4-chlorophenyl)-;Bis(4-chlorophenyl)(pyrimidin-5-yl)methanol , LY43578;Bis(4-chlorophenyl)(pyrimidin-5-yl)methanol;Pioglitazone Impurity 36 | | CAS: | 26766-35-8 | | MF: | C17H12Cl2N2O | | MW: | 331.2 | | EINECS: | | | Product Categories: | | | Mol File: | 26766-35-8.mol |  |
| | LY 43578 Chemical Properties |
| Melting point | 159-161 °C | | Boiling point | 494.9±40.0 °C(Predicted) | | density | 1.376±0.06 g/cm3(Predicted) | | form | Solid | | pka | 11.40±0.29(Predicted) | | color | White to off-white |
| | LY 43578 Usage And Synthesis |
| Description | LY 43578 is an aromatase inhibitor. | | Uses | LY43578 is an orally active aromatase inhibitor. LY43578 inhibits P-450-dependent p-nitroanisole O-demethylation and ethylmorphine N-demethylation in hepatic microsomes isolated from rat, with the IC50 of 0.3 and 5 μΜ, respectively. LY43578 can be used for neurological disorder study[1][2]. | | References | [1] Lindstrom TD, et al. Disposition of the aromatase inhibitor LY56110 and associated induction and inhibition studies in rats, dogs, and monkeys. Fundam Appl Toxicol. 1987;8(4):595-604. DOI:10.1016/0272-0590(87)90144-8
[2] Gonzalez MI, et al. Injection of an aromatase inhibitor after the critical period of sexual differentiation. Pharmacol Biochem Behav. 1994;47(1):183-186. DOI:10.1016/0091-3057(94)90129-5 |
| | LY 43578 Preparation Products And Raw materials |
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