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3-[(3-Chloro-2-methoxyphenyl)amino]-2-[3-[(2S)-1,4-dioxan-2-ylmethoxy]-4-pyridinyl]-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one

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3-[(3-Chloro-2-methoxyphenyl)amino]-2-[3-[(2S)-1,4-dioxan-2-ylmethoxy]-4-pyridinyl]-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one Suppliers list
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3-[(3-Chloro-2-methoxyphenyl)amino]-2-[3-[(2S)-1,4-dioxan-2-ylmethoxy]-4-pyridinyl]-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one manufacturers

  • Sevabertinib
  • Sevabertinib pictures
  • 2026-09-11
  • CAS:2521285-05-0
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 10 KG
3-[(3-Chloro-2-methoxyphenyl)amino]-2-[3-[(2S)-1,4-dioxan-2-ylmethoxy]-4-pyridinyl]-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one Basic information
Product Name:3-[(3-Chloro-2-methoxyphenyl)amino]-2-[3-[(2S)-1,4-dioxan-2-ylmethoxy]-4-pyridinyl]-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one
Synonyms:3-[(3-Chloro-2-methoxyphenyl)amino]-2-[3-[(2S)-1,4-dioxan-2-ylmethoxy]-4-pyridinyl]-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one;3-(3-chloro-2-methoxy-anilino)-2-[3-[[(2S)-1,4-dioxan-2-yl]methoxy]-4-pyridyl]-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one;(S)-2-[3-[(1,4-Dioxan-2-yl)methoxy]-4-pyridyl]-3-[(3-chloro-2-methoxyphenyl)amino]-6,7-dihydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-one;(S)-2-(3-((1,4-Dioxan-2-yl)methoxy)pyridin-4-yl)-3-((3-chloro-2-methoxyphenyl)amino)-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one;Dual EGFR-HER2 inhibitor Sevabertinib (BAY 2927088);Sevabertinib BAY 2927088
CAS:2521285-05-0
MF:C24H25ClN4O5
MW:484.93
EINECS:
Product Categories:API
Mol File:2521285-05-0.mol
3-[(3-Chloro-2-methoxyphenyl)amino]-2-[3-[(2S)-1,4-dioxan-2-ylmethoxy]-4-pyridinyl]-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one Structure
3-[(3-Chloro-2-methoxyphenyl)amino]-2-[3-[(2S)-1,4-dioxan-2-ylmethoxy]-4-pyridinyl]-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one Chemical Properties
Boiling point 730.8±60.0 °C(Predicted)
density 1.361±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)
pka13.38±0.20(Predicted)
InChIKeyVYQVHWNNPKOJEA-AWEZNQCLSA-N
SMILESC1(=O)NCCC2NC(C3C=CN=CC=3OC[C@@H]3COCCO3)=C(NC3=CC=CC(Cl)=C3OC)C1=2
Safety Information
MSDS Information
3-[(3-Chloro-2-methoxyphenyl)amino]-2-[3-[(2S)-1,4-dioxan-2-ylmethoxy]-4-pyridinyl]-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one Usage And Synthesis
UsesSevabertinib is an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor with antitumor activity[1].
References[1] International Nonproprietary Names for Pharmaceutical Substances (INN). WHO Drug Information, Vol. 38, No. 2, 2024.
3-[(3-Chloro-2-methoxyphenyl)amino]-2-[3-[(2S)-1,4-dioxan-2-ylmethoxy]-4-pyridinyl]-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one Preparation Products And Raw materials
Tag:3-[(3-Chloro-2-methoxyphenyl)amino]-2-[3-[(2S)-1,4-dioxan-2-ylmethoxy]-4-pyridinyl]-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one(2521285-05-0) Related Product Information
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