clomesone manufacturers
- Clomesone
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- $51.00
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2026-05-11
- CAS:88343-72-0
- Purity: 99.76%
- Supply Ability: 10g
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| | clomesone Basic information |
| Product Name: | clomesone | | Synonyms: | clomesone;(Methylsulfonyl)methanesulfonic acid 2-chloroethyl ester;Chlorethyl SOSO;NSC-338947;SRI-6155;Methanesulfonic acid, 1-(methylsulfonyl)-, 2-chloroethyl ester;2-Chloroethyl methanesulfonylmethanesulfonate;Clomesone, 10 mM in DMSO | | CAS: | 88343-72-0 | | MF: | C4H9ClO5S2 | | MW: | 236.695 | | EINECS: | | | Product Categories: | | | Mol File: | 88343-72-0.mol |  |
| | clomesone Chemical Properties |
| | clomesone Usage And Synthesis |
| Uses | Clomesone (NSC 338947) is a compound with antitumor activity. Clomesone induces the formation of cross-links between DNA strands in cell lines. Clomesone is inactive against most human colorectal cancer solid tumor cell lines in vitro, has no significant activity against mouse tumors in vivo, and is accompanied by bone marrow suppression. Its pharmacokinetic behavior indicates that it cannot reach effective concentrations at the tumor site. | | References | [1] Pre-clinical evaluation of a novel chloroethylating agent, Clomesone DOI:10.1038/bjc.1993.85
[2] M E Dolan, et al. Effect of O6-methylguanine on DNA interstrand cross-link formation by chloroethylnitrosoureas and 2-chloroethyl(methylsulfonyl)methanesulfonate. Cancer Res. 1988 Jul 1;48(13):3603-6. PMID:2837318 |
| | clomesone Preparation Products And Raw materials |
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