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eupatoriopicrine

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eupatoriopicrine Basic information
Product Name:eupatoriopicrine
Synonyms:eupatoriopicrine;(3aR,6E,10E,11aR)-3a,4,5,8,9,11a-Hexahydro-3-methylene-6,10-dimethyl-4α-[(E)-4-hydroxy-2-(hydroxymethyl)-2-butenoyloxy]cyclodeca[b]furan-2(3H)-one;(E)-4-Hydroxy-2-hydroxymethyl-2-butenoic acid (3aR,4R,6E,10E,11aR)-2,3,3a,4,5,8,9,11a-octahydro-6,10-dimethyl-3-methylene-2-oxocyclodeca[b]furan-4-yl ester;2-Butenoic acid, 4-hydroxy-2-(hydroxymethyl)-, (3aR,4R,6E,10E,11aR)-2,3,3a,4,5,8,9,11a-octahydro-6,10-dimethyl-3-methylene-2-oxocyclodeca[b]furan-4-yl ester, (2E)-
CAS:6856-01-5
MF:C20H26O6
MW:362.42
EINECS:
Product Categories:
Mol File:6856-01-5.mol
eupatoriopicrine Structure
eupatoriopicrine Chemical Properties
Boiling point 414.03°C (rough estimate)
density 1.1481 (rough estimate)
refractive index 1.4450 (estimate)
pka13.37±0.10(Predicted)
Safety Information
MSDS Information
eupatoriopicrine Usage And Synthesis
UsesEupatoriopicrin is an antitrypanosomic agent with an IC50 value of 1.2 μM (T. b. rhodesiense). Eupatoriopicrin is cytotoxic to L6 cells with an IC50 value of 1.6 μM[1].
DefinitionChEBI: Eupatoriopicrin is a germacranolide.
References[1] Julianti T, et a. Antitrypanosomal sesquiterpene lactones from Saussurea costus. Fitoterapia. 2011 Oct;82(7):955-9. DOI:10.1016/j.fitote.2011.05.010
eupatoriopicrine Preparation Products And Raw materials
Preparation ProductsEupatolide
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