E 0747 manufacturers
- E 0747
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- $293.00
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2026-04-20
- CAS:99599-78-7
- Purity: 95.17%
- Supply Ability: 10g
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| Product Name: | E 0747 | | Synonyms: | E 0747;6-Chloro-2,3-dihydro-1'-[3-(4-hydroxy-1-piperidinyl)propyl]-2,2-dimethylspiro[4H-1-benzopyran-4,4'-imidazolidine]-2',5'-dione;L-29065;6-chloro-2,2-dimethyl-1'-[3-(4-hydroxypiperidino)propyl]spiro[chroman-4,4'-imidazolidine]-2',5'-dione | | CAS: | 99599-78-7 | | MF: | C21H28ClN3O4 | | MW: | 421.91772 | | EINECS: | | | Product Categories: | | | Mol File: | 99599-78-7.mol |  |
| | E 0747 Chemical Properties |
| | E 0747 Usage And Synthesis |
| Description | E 0747 is an antiarrhythmic agent of class 1C type of the Vaughan Williams' classification. E-0747 suppresses arrhythmia by inhibiting Na channels of cardiac cells and is expected to become a clinically useful antiarrhythmic drug. | | Uses | E-0747 is an antiarrhythmic drug that inhibits arrhythmias by inhibiting Na[+] channels in cardiomyocytes[1]. | | References | [1] Mitsuhashi H, et al. Antiarrhythmic effects of a new drug, E-0747, on canine ventricular arrhythmia models. Jpn J Pharmacol. 1987 Jun;44(2):155-62. DOI:10.1254/jjp.44.155 |
| | E 0747 Preparation Products And Raw materials |
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