| Company Name: |
Alabiotech Inc. |
| Tel: |
001-619-354-5251 |
| Email: |
sales@alabiotech-e.com |
| Company Name: |
Nextpeptide Inc |
| Tel: |
+86-0571-81612335 +8613336028439 |
| Email: |
sales@nextpeptide.com |
- ES 6864
-
- $1670.00
-
2026-05-11
- CAS:116326-39-7
- Purity:
- Supply Ability: 10g
|
| | ES 6864 Basic information |
| Product Name: | ES 6864 | | Synonyms: | (3S,4S)-5-cyclohexyl-3-hydroxy-4-3-(4-thiazolyl)-L-alanyl>aMino-N-(2-Morpholinoethyl)pentanaMide|(3S,4S)-5-cyclohexyl-3-hydroxy-4{N-[2(R)-(1-naphthyl)Methyl-3-Morpholinocarbonylpropi
onyl]-3-(4-th;ES 6864;(3S,4S)-3-Hydroxy-5-cyclohexyl-4-[[(2S)-3-(4-thiazolyl)-2-[[(2R)-2-(morpholinocarbonylmethyl)-3-(1-naphthalenyl)propionyl]amino]propionyl]amino]-N-(2-morpholinoethyl)valeramide;(3S,4S)-3-Hydroxy-5-cyclohexyl-4-[[(2S)-3-(4-thiazolyl)-2-[[(2R)-2-[morpholinocarbonylmethyl]-3-(1-naphthalenyl)propionyl]amino]propionyl]amino]-N-(2-morpholinoethyl)valeramide;5-Cyclohexyl-2,4,5-trideoxy-N-[2-(4-morpholinyl)ethyl]-4-[[(2S)-2-[[(2R)-4-(4-morpholinyl)-2-(1-naphthalenylmethyl)-1,4-dioxobutyl]amino]-1-oxo-3-(4-thiazolyl)propyl]amino]-L-threo-pentonamide;L-threo-Pentonamide, 5-cyclohexyl-2,4,5-trideoxy-N-[2-(4-morpholinyl)ethyl]-4-[[(2S)-2-[[(2R)-4-(4-morpholinyl)-2-(1-naphthalenylmethyl)-1,4-dioxobutyl]amino]-1-oxo-3-(4-thiazolyl)propyl]amino]- (9CI) | | CAS: | 116326-39-7 | | MF: | C42H58N6O7S | | MW: | 791.01 | | EINECS: | | | Product Categories: | Pepetides;peptides | | Mol File: | 116326-39-7.mol |  |
| | ES 6864 Chemical Properties |
| Boiling point | 1088.525±65.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.243±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | pka | 13.301±0.46(predicted) |
| | ES 6864 Usage And Synthesis |
| Description | ES 6864 is an orally active renin inhibitor. | | Uses | ES 6864 is an orally active, competitive inhibitor for human renin, with an IC50 of 6.9 nM and a Ki of 7.3 nM. ES 6864 exhibits high species-specific and enzyme-specific properties. ES 6864 exhibits metabolic stability in rat tissue homogenates. ES 6864 reduces blood pressure in rats and sodium-depleted awake marmosets[1]. | | References | [1] Hiwada K, et al., A highly potent and long-acting oral inhibitor of human renin. Hypertension. 1988 Jun;11(6 Pt 2):708-12. DOI:10.1161/01.hyp.11.6.708 |
| | ES 6864 Preparation Products And Raw materials |
|