5-[(2,4-Dioxo-1,3-thiazolidin-5-yl)methyl]-2-methoxy-N-[4-(trifluoromethyl)benzyl]benzamide

Request For Quotation
5-[(2,4-Dioxo-1,3-thiazolidin-5-yl)methyl]-2-methoxy-N-[4-(trifluoromethyl)benzyl]benzamide Suppliers list
Company Name: BOC Sciences  
Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Company Name: ShangHai Onsyn-Chemical Technology Co., Ltd.  
Tel: 13917628136 15900795984
Email: 572350448@qq.com
Company Name: ShangHai Caerulum Pharma Discovery Co., Ltd.  
Tel: 18149758185 18149758185
Email: sales-cpd@caerulumpharma.com
Company Name: Shanghai EFE Biological Technology Co., Ltd.  
Tel: 021-65675885 18964387627
Email: info@efebio.com
Company Name: TargetMol Chemicals Inc.  
Tel: +1-781-999-5354; +1-00000000000
Email: marketing@targetmol.com

5-[(2,4-Dioxo-1,3-thiazolidin-5-yl)methyl]-2-methoxy-N-[4-(trifluoromethyl)benzyl]benzamide manufacturers

  • KRP-297
  • KRP-297 pictures
  • $760.00
  • 2026-07-27
  • CAS:213252-19-8
  • Purity:
  • Supply Ability: 10g
5-[(2,4-Dioxo-1,3-thiazolidin-5-yl)methyl]-2-methoxy-N-[4-(trifluoromethyl)benzyl]benzamide Basic information
Product Name:5-[(2,4-Dioxo-1,3-thiazolidin-5-yl)methyl]-2-methoxy-N-[4-(trifluoromethyl)benzyl]benzamide
Synonyms:5-[(2,4-dioxothiazolidin-5-yl)Methyl]-2-Methoxy-N-[[4-(trifluoroMethyl)phenyl]Methyl]benzaMide;Benzamide, 5-[(2,4-dioxo-5-thiazolidinyl)methyl]-2-methoxy-N-[[4-(trifluoromethyl)phenyl]methyl]-;L 410198;L410198;5-[(2,4-Dioxo-1,3-thiazolidin-5-yl)methyl]-2-methoxy-N-[4-(trifluoromethyl)benzyl]benzamide
CAS:213252-19-8
MF:C20H17F3N2O4S
MW:438.42
EINECS:
Product Categories:
Mol File:213252-19-8.mol
5-[(2,4-Dioxo-1,3-thiazolidin-5-yl)methyl]-2-methoxy-N-[4-(trifluoromethyl)benzyl]benzamide Structure
5-[(2,4-Dioxo-1,3-thiazolidin-5-yl)methyl]-2-methoxy-N-[4-(trifluoromethyl)benzyl]benzamide Chemical Properties
storage temp. -20°C
solubility DMSO: 10 mg/ml
form A solid
Safety Information
MSDS Information
5-[(2,4-Dioxo-1,3-thiazolidin-5-yl)methyl]-2-methoxy-N-[4-(trifluoromethyl)benzyl]benzamide Usage And Synthesis
UsesKRP-297 is a PPARα and PPARγ agonist potentially for the research of type 2 diabetes and dyslipidemia. KRP-297 restores reduced lipid oxidation, and inhibits of enhanced lipogenesis and triglyceride accumulation in the liver.
Biological ActivityKRP 927 is a thiazolidinedione dual agonist of PPARα and PPARγ (EC50s = 149 and 83 nM, respectively, in transactivation assays).1 It decreases hyperglycemia and hyperinsulinemia in ob/ob mice in a dose-dependent manner. KRP 927 (10 or 30 mg/kg) reduces serum total cholesterol and triglyceride levels in hamsters.
References1.Doebber, T.W., Kelly, L.J., Zhou, G., et al.MK-0767, a novel dual PPARα/γ agonist, displays robust antihyperglycemic and hypolipidemic activitiesBiochem. Biophys. Res. Commun.318(2)323-328(2004)
5-[(2,4-Dioxo-1,3-thiazolidin-5-yl)methyl]-2-methoxy-N-[4-(trifluoromethyl)benzyl]benzamide Preparation Products And Raw materials
Tag:5-[(2,4-Dioxo-1,3-thiazolidin-5-yl)methyl]-2-methoxy-N-[4-(trifluoromethyl)benzyl]benzamide(213252-19-8) Related Product Information
5-[(2,6-dimethoxyphenyl)methyl]-1,3-thiazolidine-2,4-dione MK 0767 5-[(2,4-Dioxo-1,3-thiazolidin-5-yl)methyl]-2-methoxy-N-[4-(trifluoromethyl)benzyl]benzamide Pioglitazone EP IMpurity F 5-(2-Hydroxy-3-methoxybenzyl)-1,3-thiazolane-2,4-dione HWL-088