12alpha-HYDROXYROTENONE manufacturers
- Rotenolone
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- $313.00
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2026-05-11
- CAS:509-96-6
- Purity: 99.27%
- Supply Ability: 10g
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| | 12alpha-HYDROXYROTENONE Basic information |
| Product Name: | 12alpha-HYDROXYROTENONE | | Synonyms: | (2R)-1,2,12,12aα-Tetrahydro-6aα-hydroxy-2α-isopropenyl-8,9-dimethoxy-[1]benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one;(2R)-2α-(1-Methylvinyl)-6aα-hydroxy-8,9-dimethoxy-1,2,6,6a,12,12aα-hexahydro[1]benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6-one;(2R)-6aα-Hydroxy-1,2,12,12aα-tetrahydro-2α-isopropenyl-8,9-dimethoxy[1]benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one;12a-Hydroxyrotenone;12α-Hydroxyrotenone;Rotenolone I;(1)Benzopyrano(3,4-B)furo(2,3-H)(1)benzopyran-6(6ah)-one, 1,2,12,12A-alpha-tetrahydro-6A-alpha-hydroxy-2-alpha-isopropenyl-8,9-dimethoxy-;6A-beta,12A-beta-Rotenolone | | CAS: | 509-96-6 | | MF: | C23H22O7 | | MW: | 410.42 | | EINECS: | | | Product Categories: | Miscellaneous Natural Products;Iso-Flavones | | Mol File: | 509-96-6.mol |  |
| | 12alpha-HYDROXYROTENONE Chemical Properties |
| Melting point | 140-141 °C | | Boiling point | 623.1±55.0 °C(Predicted) | | density | 1.358±0.06 g/cm3(Predicted) | | pka | 10.48±0.40(Predicted) | | form | Solid | | color | White to off-white |
| | 12alpha-HYDROXYROTENONE Usage And Synthesis |
| Uses | Rotenolone is an antiproliferative agent. Rotenolone shows antiproliferative activity against the ovarian cancer A2780, breast cancer BT-549, prostate cancer DU 145, NSCLC NCI-H460, and colon cancer HCC-2998 cell lines, with IC50s of 0.95, 1.6, 2.7, 2.0, and 2.9 μM, respectively[1]. | | Definition | ChEBI: 12a-hydroxyrotenone is an organic molecular entity. It has a role as a metabolite. | | References | [1] Harinantenaina L, et, al. Antiproliferative compounds from Pongamiopsis pervilleana from the Madagascar Dry Forest. J Nat Prod. 2010 Sep 24;73(9):1559-62. DOI:10.1021/np100430r |
| | 12alpha-HYDROXYROTENONE Preparation Products And Raw materials |
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