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| | hydrochloride Basic information |
| Product Name: | hydrochloride | | Synonyms: | 2-[[4-[4-(2-methoxyphenyl)piperidin-1-yl]-2-(1-methylcyclopropyl)quinazolin-6-yl]-methylamino]ethanol;Ethanol, 2-[[4-[4-(2-methoxyphenyl)-1-piperidinyl]-2-(1-methylcyclopropyl)-6-quinazolinyl]methylamino]-, hydrochloride (1:1);SBI-810 HCI;SBI-810 HCl | | CAS: | 2772746-58-2 | | MF: | C27H34N4O2.ClH | | MW: | 483.05 | | EINECS: | | | Product Categories: | | | Mol File: | 2772746-58-2.mol |  |
| | hydrochloride Chemical Properties |
| form | Solid | | color | Light yellow to yellow |
| | hydrochloride Usage And Synthesis |
| Uses | SBI-810 hydrochloride is a functionally selected β-arrestin-biased neurotensin receptor 1 (NTSR1) allosteric modulator. SBI-810 hydrochloride modulates NTSR1 G protein signaling in a G protein-specific manner in the presence of the endogenous ligand, neurotensin (NT). SBI-810 hydrochloride fully antagonizes NT-induced activation of Gq, partially antagonizes NT-induced activation of Gi1 and is permissive of NTSR1 activation of GoA and G12[1][2]. | | References | [1] Lawrence Barak, et al. Compositions for and methods of treating and/or preventing pain. WO2022241186A1. 2022 November 17.
[2] Center M N A, et al. Summer Undergraduate Research Expo[J]. 2014. |
| | hydrochloride Preparation Products And Raw materials |
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