Tat-CIRP (trifluoroacetate salt)

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Tat-CIRP (trifluoroacetate salt) Suppliers list
Company Name: Cayman Chemical Company  
Tel: 800-364-9897
Email: sales@caymanchem.com
Company Name: Neobioscience Co., Ltd.  
Tel: 4006-800-892
Email: info@neobioscience.com
Tat-CIRP (trifluoroacetate salt) Basic information
Product Name:Tat-CIRP (trifluoroacetate salt)
Synonyms:Tat-CIRP (trifluoroacetate salt)
CAS:
MF:
MW:0
EINECS:
Product Categories:
Mol File:Mol File
Tat-CIRP (trifluoroacetate salt) Structure
Tat-CIRP (trifluoroacetate salt) Chemical Properties
solubility Water: soluble
Safety Information
MSDS Information
Tat-CIRP (trifluoroacetate salt) Usage And Synthesis
DescriptionTat-CIRP is a peptide inhibitor of the protein-protein interaction between myeloid differentiation 2 (MD-2), also known as lymphocyte antigen 96 (LY96), and cold-inducible RNA binding protein (CIRP).1 It binds to MD-2 and disrupts the interaction between MD-2 and CIRP in co-immunoprecipitation assays. In vivo, Tat-CIRP (10 and 20 mg/kg) reduces infarct volume in a mouse model of stroke induced by middle cerebral artery occlusion (MCAO). It also reduces infarct volume and decreases the time to pick up and withdraw food with the stroke-affected arm in a rhesus monkey model of thrombosis-induced stroke.WARNING This product is not for human or veterinary use.
References[1] ZONGPING FANG. An MD2-perturbing peptide has therapeutic effects in rodent and rhesus monkey models of stroke[J]. Science Translational Medicine, 2021, 13 597. DOI: 10.1126/scitranslmed.abb6716
Tat-CIRP (trifluoroacetate salt) Preparation Products And Raw materials
Tag:Tat-CIRP (trifluoroacetate salt) Related Product Information
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