Ac-VDVAD-AFC (trifluoroacetate salt)

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Ac-VDVAD-AFC (trifluoroacetate salt) Suppliers list
Company Name: Cayman Chemical Company  
Tel: 800-364-9897
Email: sales@caymanchem.com
Company Name: Neobioscience Co., Ltd.  
Tel: 4006-800-892
Email: info@neobioscience.com
Ac-VDVAD-AFC (trifluoroacetate salt) Basic information
Product Name:Ac-VDVAD-AFC (trifluoroacetate salt)
Synonyms:Ac-VDVAD-AFC (trifluoroacetate salt)
CAS:
MF:
MW:0
EINECS:
Product Categories:
Mol File:Mol File
Ac-VDVAD-AFC (trifluoroacetate salt) Structure
Ac-VDVAD-AFC (trifluoroacetate salt) Chemical Properties
solubility Water: Soluble
Safety Information
MSDS Information
Ac-VDVAD-AFC (trifluoroacetate salt) Usage And Synthesis
DescriptionAc-VDVAD-AFC is a fluorogenic substrate for caspase-2.1,2 Upon enzymatic cleavage by caspase-2, 7-amino-4-trifluoromethylcoumarin (AFC) is released and its fluorescence can be used to quantify caspase-2 activity. AFC displays excitation/emission maxima of 400/505 nm, respectively.WARNING This product is not for human or veterinary use.
References[1] RYUICHI MORIYA  Yasuyuki N  Takashi Uehara. Mechanism of nitric oxide-induced apoptosis in human neuroblastoma SH-SY5Y cells[J]. FEBS Letters, 2000, 484 3: 253-260. DOI: 10.1016/s0014-5793(00)02167-0
[2] R V TALANIAN. Substrate specificities of caspase family proteases.[J]. The Journal of Biological Chemistry, 1997, 272 15: 9677-9682. DOI: 10.1074/jbc.272.15.9677
Ac-VDVAD-AFC (trifluoroacetate salt) Preparation Products And Raw materials
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