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| | BBO-10203 Basic information |
| Product Name: | BBO-10203 | | Synonyms: | BBO-10203;1-(2-(7-(2,4-Difluoro-6-(2-methoxyethoxy)phenyl)-4-(1-methyl-1H-indazol-5-yl)thieno[3,2-c]pyridin-6-yl)-4-methyl-6,7-dihydropyrazolo[1,5-a]pyrazin-5(4H)-yl)prop-2-en-1-one | | CAS: | 2971769-60-3 | | MF: | C34H30F2N6O3S | | MW: | 640.7 | | EINECS: | | | Product Categories: | | | Mol File: | 2971769-60-3.mol |  |
| | BBO-10203 Chemical Properties |
| Boiling point | 774.046±60.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.415±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | pka | 1.181±0.10(predicted) |
| | BBO-10203 Usage And Synthesis |
| Uses | BBO-10203 (Compound 758) binds to the RBD region of PI3Kα, and inhibits the binding of K-, H-, and N-Ras to PI3Kα. BBO-10203 inhibits pAKT with an IC50 < 0.1 pM in BT474 cell[1]. | | References | [1] Xu R. et al., Compounds having a t-structure formed by at least four cycles for use in the treatment of cancer and other indications. WO2023154282. |
| | BBO-10203 Preparation Products And Raw materials |
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Tag:BBO-10203(2971769-60-3)
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