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| | 7-Bromo-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-Benzodiazepin-2-one Basic information |
| Product Name: | 7-Bromo-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-Benzodiazepin-2-one | | Synonyms: | 2H-1,4-BENZODIAZEPIN-2-ONE, 7-BROMO-5-(2-CHLOROPHENYL)-1,3-DIHYDRO-;7-BROMO-5-[O-CHLOROPHENYL]-1,3-DIHYDRO-2H-1,4-BENZODIAZEPIN-2-ONE;7-BROMO-5-(2-CHLORO-PHENYL)-1,3-DIHYDRO-2H-1,4-BENZODIAZEPIN-2-ONE;IFLAB-BB F0133-0017;1,3-dihydro-7-bromo-5-(2-chlorophenyl)-2h-4-benzodiazepin-2-one;7-bromo-5-(2-chlorophenyl)-1,3-dihydro-2h-4-benzodiazepin-2-one;bd98;fenazepam | | CAS: | 51753-57-2 | | MF: | C15H10BrClN2O | | MW: | 349.61 | | EINECS: | 682-231-2 | | Product Categories: | Psychopathic Drugs;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;CJC | | Mol File: | 51753-57-2.mol |  |
| | 7-Bromo-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-Benzodiazepin-2-one Chemical Properties |
| Melting point | 214-224°C | | Boiling point | 493.0±45.0 °C(Predicted) | | density | 1.61±0.1 g/cm3(Predicted) | | Fp | 2℃ | | storage temp. | Controlled Substance, -20°C Freezer | | solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) | | pka | 11.58±0.70(Predicted) | | form | Solid | | color | Pale Yellow | | Major Application | clinical testing | | InChI | 1S/C15H10BrClN2O/c16-9-5-6-13-11(7-9)15(18-8-14(20)19-13)10-3-1-2-4-12(10)17/h1-7H,8H2,(H,19,20) | | InChIKey | CGMJQQJSWIRRRL-UHFFFAOYSA-N | | SMILES | Clc1ccccc1C2=NCC(=O)Nc3ccc(Br)cc23 | | CAS DataBase Reference | 51753-57-2(CAS DataBase Reference) |
| Hazard Codes | F,Xn | | Risk Statements | 11-20/21/22-36 | | Safety Statements | 16-36/37 | | RIDADR | UN 1648 3 / PGII | | WGK Germany | 2 | | Storage Class | 3 - Flammable liquids | | Hazard Classifications | Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Irrit. 2
Flam. Liq. 2
Muta. 1B | | Toxicity | LD50 ipr-rat: 720 mg/kg KHFZAN 13(10),108,79 |
| | 7-Bromo-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-Benzodiazepin-2-one Usage And Synthesis |
| Description | Phenazepam (CRM) (Item No. ISO60172) is a certified reference material categorized as a benzodiazepine. It has sedative and hypnotic properties and has been detected in illicit tablets. This product is intended for research and forensic applications. | | Chemical Properties | 7-Bromo-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-Benzodiazepin-2-one is Pale Yellow Solid | | Uses | 7-Bromo-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-Benzodiazepin-2-one is used in the treatment of neurological disorders such as epilepsy, alcohol withdrawal and insomnia. It can be used as a premedication before surgery as it augments the effects of anesthetics and reduces anxiety | | General Description | Phenazepam, a benzodiazepine drug produced in Russia, is used in Europe as an anxiolytic, anticonvulsant, and muscle relaxant. Although not used therapeutically in the US, the drug can be purchased on the internet for “laboratory research” purposes. Cases of abuse have been reported from European countries such as Sweden and Russia to states including New York, Kentucky, North Carolina, and Georgia. | | Safety Profile | Moderately toxic by ingestion and intraperitoneal routes. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of Clí, Brí, and NOx. | | References | [1] De Souza, F.I., Zumiotti, A.V., and Da Silva, C.F. Neuregulins 1-α and 1-β on the regeneration the peripheral nerves[J]. Acta Ortop Bras.
[2] OYEMADE A. New uncontrolled benzodiazepine, phenazepam, emerging drug of abuse.[J]. Innovations in clinical neuroscience, 2012, 9 9: 10.
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| | 7-Bromo-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-Benzodiazepin-2-one Preparation Products And Raw materials |
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