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| | 6-(4-{2-[3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-2-methylene-cyclohexylidene]-ethylidene}-7a-methyl-octahydro-inden-1-yl)-2-methyl-heptan-2-ol Basic information |
| Product Name: | 6-(4-{2-[3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-2-methylene-cyclohexylidene]-ethylidene}-7a-methyl-octahydro-inden-1-yl)-2-methyl-heptan-2-ol | | Synonyms: | 6-(4-{2-[3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-2-methylene-cyclohexylidene]-ethylidene}-7a-methyl-octahydro-inden-1-yl)-2-methyl-heptan-2-ol;(R)-6-((1R,3aS,7aR,E)-4-((Z)-2-((3S,5R)-3,5-bis(tert-butyldiMethylsilyloxy)-2-Methylenecyclohexylidene)ethylidene)-7a-Methyloctahydro-1H-inden-1-yl)-2-Methylheptan-2-ol;(1S),3(R)-bis<(tert-butyldimethylsilyl)oxy>-9,10-secocholesta-5(Z),7(E),10(19)-trien-25-ol;(R)-6 - ((1R,3AS,7AR,E)-4 - ((Z)-2 - ((3S,5R)-3,5-;(1S,3R,5Z,7E,14)-1,3-Bis{[tert-butyl(dimethyl)silyl]oxy}-9,10-secocholesta-5,7,10-trien-25-ol;Calcitriol Impurity 12;9,10-Secocholesta-5,7,10(19)-trien-25-ol, 1,3-bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-, (1α,3β,5Z,7E)- (9CI);(R)-6-((1R,3As,7Ar,E)-4-((Z)-2-((3R,5S)-3,5-Bis((Tert-Butyldimethylsilyl)Oxy)-2-Methylenecyclohexylidene)Ethylidene)-7A-Methylctahydro-1H-Inden-1-Yl)-2-Methylheptan-2-ol | | CAS: | 140710-96-9 | | MF: | C39H72O3Si2 | | MW: | 645.16 | | EINECS: | | | Product Categories: | | | Mol File: | 140710-96-9.mol | ![6-(4-{2-[3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-2-methylene-cyclohexylidene]-ethylidene}-7a-methyl-octahydro-inden-1-yl)-2-methyl-heptan-2-ol Structure](CAS/GIF/140710-96-9.gif) |
| | 6-(4-{2-[3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-2-methylene-cyclohexylidene]-ethylidene}-7a-methyl-octahydro-inden-1-yl)-2-methyl-heptan-2-ol Chemical Properties |
| Boiling point | 621.9±55.0 °C(Predicted) | | density | 0.95±0.1 g/cm3(Predicted) | | pka | 15.32±0.29(Predicted) |
| | 6-(4-{2-[3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-2-methylene-cyclohexylidene]-ethylidene}-7a-methyl-octahydro-inden-1-yl)-2-methyl-heptan-2-ol Usage And Synthesis |
| Uses | 6-(4-{2-[3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-2-methylene-cyclohexylidene]-ethylidene}-7a-methyl-octahydro-inden-1-yl)-2-methyl-heptan-2-ol is an Impurity of calcitriol, a medication that treats low calcium levels caused by kidney disease.
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| | 6-(4-{2-[3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-2-methylene-cyclohexylidene]-ethylidene}-7a-methyl-octahydro-inden-1-yl)-2-methyl-heptan-2-ol Preparation Products And Raw materials |
| Raw materials | 1-Octen-7-yne-3,5-diol, (3S,5R)--->1H-Indene-1-pentanol, 4-(bromomethylene)octahydro-α,α,ε,7a-tetramethyl-, (εR,1R,3aR,4E,7aR)--->(5R,7S)-2,2,3,3,9,9,10,10-octamethyl-5-(prop-2-ynyl)-7-vinyl-4,8-dioxa-3,9-disilaundecane-->(S)-2-((1R,3aS,7aR,E)-4-((E)-2-((3S,5R)-3,5-bis(tert-butyldiMethylsilyloxy)-2-Methylenecyclohexylidene)ethylidene)-7a-Methyloctahydro-1H-inden-1-yl)propan-1-ol-->Calcitriol-->2,3,3a,6,7,7a-Hexahydro-2S,7a-diMethyl-4-hydroxy-indene-1R-(1'-iodo)ethane 4-O-TrifluoroMethylsulfonate-->2,3,3a,6,7,7a-Hexahydro-5',7a-diMethyl-4-hydroxy-indene-(1R)-1'-pentanoic Acid Methyl Ester 4-O-TrifluoroMethanesulfonate-->(1R,1'S)-Octahydro-1-(2'-iodo-1'-Methylethyl)-7a-Methyl-inden-4-one-->1-(2-Hydroxy-1-methyl-ethyl)-7a-methyl-octahydro-inden-4-ol-->(1R,3aR,4S,7aR)-Octahydro-1-[(1S)-2-iodo-1-methylethyl]-7a-methyl-1H-inden-4-ol-->(3S)-1,3-Bis-O-tert-ButyldiMethylsilyl 3-Hydroxy VitaMin D2 SO2 Adduct (Mixture of DiastereoMers)-->(6R)-6-((1R,3aS,7aR)-4-((E)-2-((3S,5R)-3,5-bis(tert-butyldiMethylsilyloxy)-2-Methylenecyclohexylidene)ethyl)-7a-Methyloctahydro-1H-inden-1-yl)-2-Methylheptan-2-ol-->tert-Butyldimethylsilyl chloride-->Trifluoromethanesulfonic acid tert-butyldimethylsilyl ester |
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