H-Glu-Ala-Ala-Gly-Ile-Gly-Ile-Leu-Thr-Val-OH manufacturers
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| | H-Glu-Ala-Ala-Gly-Ile-Gly-Ile-Leu-Thr-Val-OH Basic information |
| Product Name: | H-Glu-Ala-Ala-Gly-Ile-Gly-Ile-Leu-Thr-Val-OH | | Synonyms: | GLU-ALA-ALA-GLY-ILE-GLY-ILE-LEU-THR-VAL;EAAGIGILTV;ANTIGEN SK29-AA (26-35) (HUMAN);ANTIGEN LB39-AA (26-35) (HUMAN);MART-1 (26-35) (HUMAN);MELANOMA ANTIGEN RECOGNIZED BY T-CELLS 1 (26-35) (HUMAN);MELAN-A PROTEIN (26-35) (HUMAN);MELAN-A | | CAS: | 156251-01-3 | | MF: | C42H74N10O14 | | MW: | 943.1 | | EINECS: | | | Product Categories: | peptide | | Mol File: | 156251-01-3.mol |  |
| | H-Glu-Ala-Ala-Gly-Ile-Gly-Ile-Leu-Thr-Val-OH Chemical Properties |
| Boiling point | 1358.4±65.0 °C(Predicted) | | density | 1.223±0.06 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | water, double-distilled: soluble | | pka | 3.32±0.10(Predicted) | | form | lyophilized powder | | color | white | | Water Solubility | water, double-distilled: soluble | | Sequence | Glu-Ala-Ala-Gly-Ile-Gly-Ile-Leu-Thr-Val |
| WGK Germany | WGK 3 | | Storage Class | 11 - Combustible Solids |
| | H-Glu-Ala-Ala-Gly-Ile-Gly-Ile-Leu-Thr-Val-OH Usage And Synthesis |
| Uses | MART-1 (26-35) (human) is amino acid residue 26 to 35 of MART-1 protein. | | Biological Activity | Melanoma-associated antigen recognized by T cells-1 (MART-1) is essential for the functioning of glycoprotein-100 (gp100). Overexpression of the gene has been observed in cutaneous melanoma (CM). In addition, deletion of Mart-1 gene leads to parotid metastatic melanoma. | | References | [1] Coulie PG, et al. A new gene coding for a differentiation antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas. J Exp Med. 1994 Jul 1;180(1):35-42. DOI:10.1084/jem.180.1.35
[2] Borbulevych OY, et al. Structures of MART-126/27-35 Peptide/HLA-A2 complexes reveal a remarkable disconnect between antigen structural homology and T cell recognition. J Mol Biol. 2007 Oct 5;372(5):1123-36. DOI:10.1016/j.jmb.2007.07.025 |
| | H-Glu-Ala-Ala-Gly-Ile-Gly-Ile-Leu-Thr-Val-OH Preparation Products And Raw materials |
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