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2-Methylhydroquinone

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CAS:95-71-6
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CAS:95-71-6
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CAS:95-71-6
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Products Intro: Product Name:2-Methylhydroquinone
CAS:95-71-6

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2-Methylhydroquinone Basic information
Product Name:2-Methylhydroquinone
Synonyms:2-METHYLHYDROQUINONE;2-METHYL-1,4-BENZENEDIOL;2,5-DIHYDROXYTOLUENE;P-TOLUHYDROQUINONE;3-METHYL-1,4-DIHYDROXYBENZENE;1,4-Dihydroxy-2-methylbenzene;2-Methyl-benzene-1,4-diol;METHYLHYDROQUINONE, 99+%
CAS:95-71-6
MF:C7H8O2
MW:124.14
EINECS:202-443-7
Product Categories:Building Blocks;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds;Polyols;Anthraquinones, Hydroquinones and Quinones;Intermediates of Dyes and Pigments;intermediate;bc0001;95-71-6
Mol File:95-71-6.mol
2-Methylhydroquinone Structure
2-Methylhydroquinone Chemical Properties
Melting point 128-130 °C(lit.)
Boiling point 285°C
density 1.1006 (rough estimate)
vapor pressure 0.004Pa at 25℃
refractive index 1.4922 (estimate)
Fp 172 °C
storage temp. Store below +30°C.
solubility 77g/l
form Crystalline Powder
pkapK1:10.03;pK2:11.62 (25°C)
color Grayish-white to light beige
Water Solubility 77 g/L (25 ºC)
BRN 2041489
Stability:Stable. Combustible. Incompatible with oxidizing agents, strong bases.
InChI1S/C7H8O2/c1-5-4-6(8)2-3-7(5)9/h2-4,8-9H,1H3
InChIKeyCNHDIAIOKMXOLK-UHFFFAOYSA-N
SMILESCc1cc(O)ccc1O
LogP0.9 at 27℃
CAS DataBase Reference95-71-6(CAS DataBase Reference)
NIST Chemistry Reference1,4-Benzenediol, 2-methyl-(95-71-6)
EPA Substance Registry System2-Methylhydroquinone (95-71-6)
Safety Information
Hazard Codes Xi,Xn
Risk Statements 36/37/38-22
Safety Statements 26-36
RIDADR 2811
WGK Germany 2
RTECS MX6700000
Autoignition Temperature851 °F
TSCA TSCA listed
HazardClass 6.1(b)
PackingGroup III
HS Code 29072900
Storage Class8A - Combustible corrosive hazardous materials
Hazard ClassificationsAquatic Acute 1
Aquatic Chronic 1
Eye Dam. 1
Skin Corr. 1A
Skin Sens. 1
STOT SE 3
ToxicityLD50 orally in Rabbit: 200 - 400 mg/kg
MSDS Information
ProviderLanguage
2,5-Dihydroxytoluene English
SigmaAldrich English
ACROS English
ALFA English
2-Methylhydroquinone Usage And Synthesis
Chemical Propertieswhite solid
UsesAntioxidant, polymerization inhibitor.
UsesMethylhydroquinone is used as stabilizer and antioxidant in aerylic monomers to prevent polymerization.
UsesMethylhydroquinone is a marine fungus metabolite, showing activity as an angiosupressor that interferes with the Akt pathway. Allows for screening of novel inhibitors of angiogenesis.
DefinitionChEBI: A member of the class of hydroquinones that is hydroquinone in which one of the benzene hydrogens has been replaced by a methyl group.
Synthesis Reference(s)Tetrahedron, 44, p. 1227, 1988 DOI: 10.1016/S0040-4020(01)85902-0
Tetrahedron Letters, 22, p. 2337, 1981 DOI: 10.1016/S0040-4039(01)82900-2
General DescriptionMethylhydroquinone is produced by the oxidation of o-cresol by the mutants G103S, G103S/A107G, and G103S/A107T.
Flammability and ExplosibilityNot classified
Biochem/physiol ActionsMethylhydroquinone (Toluquinol) inhibits the growth of endothelial and tumor cells in culture in the micromolar range and is a promising drug candidate in the treatment of cancer and other angiogenesis-related pathologies.
Purification MethodsCrystallise the quinone from EtOH. [Beilstein 6 IV 5866.]
Tag:2-Methylhydroquinone(95-71-6) Related Product Information
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