CAY10576

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CAY10576 manufacturers

  • GSK319347A
  • GSK319347A pictures
  • $64.00
  • 2026-07-14
  • CAS:862812-98-4
  • Purity: 98.42%
  • Supply Ability: 10g
CAY10576 Basic information
Product Name:CAY10576
Synonyms:CAY10576;IKK-3 Inhibitor;2-Thiophenecarbonitrile, 5-(5,6-diMethoxy-1H-benziMidazol-1-yl)-3-[[2-(Methylsulfonyl)phenyl]Methoxy]-;5-(5,6-Dimethoxy-1H-benzimidazol-1-yl)-3-[[2-(methylsulfonyl)phenyl]methoxy]-2-thiophenecarbonitrile;5-(5,6-dimethoxybenzimidazol-1-yl)-3-[(2-methylsulfonylphenyl)methoxy]thiophene-2-carbonitrile;GSK-319347A,GSK319347A;IKK-epsilon Kinase Inhibitor II, Inhibitor of IkappaB kinases (IKK);GSK319347A, 10 mM in DMSO
CAS:862812-98-4
MF:C22H19N3O5S2
MW:469.53
EINECS:
Product Categories:
Mol File:862812-98-4.mol
CAY10576 Structure
CAY10576 Chemical Properties
Boiling point 744.4±70.0 °C(Predicted)
density 1.39±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 45 mg/mL (95.84 mM; Need ultrasonic)
form Powder
pka3.09±0.10(Predicted)
color Light yellow to yellow
InChI1S/C22H19N3O5S2/c1-28-17-8-15-16(9-18(17)29-2)25(13-24-15)22-10-19(20(11-23)31-22)30-12-14-6-4-5-7-21(14)32(3,26)27/h4-10,13H,12H2,1-3H3
InChIKeyLDTAHRLHGHFHKP-UHFFFAOYSA-N
Safety Information
WGK Germany WGK 2
Storage Class11 - Combustible Solids
MSDS Information
CAY10576 Usage And Synthesis
UsesGSK 319347A is a potent and selective IKKε kinase inhibitor.
DefinitionChEBI: 5-(5,6-dimethoxy-1-benzimidazolyl)-3-[(2-methylsulfonylphenyl)methoxy]-2-thiophenecarbonitrile is a member of benzimidazoles.
Biological ActivityCell permeable: no', 'Primary Target
IKK-3', 'Product competes with ATP.', 'Reversible: no', 'Target IC50: 40 nM against IKK-3 (IKK-ε)
IC 50TBK1: 93 nM (IC50); IKK-ε: 469 nM (IC50); IKK2: 790 nM (IC50)
storageStore at -20°C
CAY10576 Preparation Products And Raw materials
Tag:CAY10576(862812-98-4) Related Product Information
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