| Company Name: |
Sigma-Aldrich |
| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
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| | ω-Agatoxin TK Basic information |
| Product Name: | ω-Agatoxin TK | | Synonyms: | Ω-AGATOXIN TK;Cys14-Cys33;Cys18-Cys35);H-Gly-Val-Pro-Ile-Asn-Val-Ser-Cys-Thr-Gly-Ser-Pro-Gln-Cys-Ile-Lys-Pro-Cys-Lys-Asp-Ala-Gly-Met-Arg-Phe-Gly-Lys-Cys-Met-Asn-Arg-Lys-Cys-His-Cys-Thr-Pro-Lys-OH(Disulfide bridge：Cys8-Cys28 | | CAS: | 158484-42-5 | | MF: | C215H337N65O70S10 | | MW: | 5273.01978 | | EINECS: | | | Product Categories: | | | Mol File: | 158484-42-5.mol |  |
| | ω-Agatoxin TK Chemical Properties |
| storage temp. | -20°C | | solubility | H2O: soluble (Aqueous stock solution is stable for 1 month at 2-8°C and for several months at -20°C.) | | form | powder | | color | White to off-white | | Water Solubility | Soluble in water | | Sequence | Glu-Asp-Asn-Cys-Ile-Ala-Glu-Asp-Tyr-Gly-Lys-Cys-Thr-Trp-Gly-Gly-Thr-Lys-Cys-Cys-Arg-Gly-Arg-Pro-Cys-Arg-Cys-Ser-Met-Ile-Gly-Thr-Asn-Cys-Glu-Cys-Thr-Pro-Arg-Leu-Ile-Met-Glu-Gly-Leu-Ser-Phe-Ala (Disulfide bridge:Cys4-Cys20,Cys12-Cys25,Cys19-Cys36,Cys27-Cys34) |
| WGK Germany | 3 | | Storage Class | 11 - Combustible Solids |
| | ω-Agatoxin TK Usage And Synthesis |
| Uses | omega-Agatoxin TK is a selective blocker of the P-type Ca2+channel. | | Biochem/physiol Actions | Toxin found in the venom of the funnel web spider, Agelenopsis aptera. Potent, selective P-type and Q-type calcium-channel blocker, without effect on L-type, N-type, or T-type calcium channels. Used to differentiate the types of calcium channel active during various physiological processes | | IC 50 | P/Q-type calciumchannel | | storage | -20°C (desiccate) |
| | ω-Agatoxin TK Preparation Products And Raw materials |
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